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4-Aminobenzamide

CAS 2835-68-9H2NC6H4CONH2Chemical Synthesis

4-Aminobenzamide (CAS 2835-68-9) is an organic compound with the molecular formula C <sub>7</sub>H <sub>8</sub>N <sub>2</sub>O. As a derivative of benzamide, it features both an amine and an amide functional group. This compound is primarily recognised for its role as a poly(ADP-ribose)polymerase (PARP) inhibitor. It is utilized in biochemical research to investigate cellular processes involving DNA repair and cell death mechanisms, making it a valuable tool for scientific inquiry.

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4-Aminobenzamide (H2NC6H4CONH2) — chemical structure, CAS 2835-68-9; Chemistry, fine chemical supplied by Tech Serve Solutions
AmidesBuilding BlocksC2 to C7Carbonyl CompoundsChemical Synthesis
01 /Applications

PARP Inhibition in Research

4-Aminobenzamide serves as a key reagent in studies exploring the function of the nuclear enzyme poly(ADP-ribose)polymerase (PARP). Its inhibitory action allows researchers to elucidate the role of PARP in cellular processes such as DNA repair and cell death.

Biochemical Studies

This compound is employed in various biochemical assays to understand the intricate pathways regulated by PARP. It aids in the investigation of targeted cell death induced by cytotoxic effector cells.

Organic Synthesis Building Block

As a functionalized aromatic compound, 4-Aminobenzamide can serve as a versatile building block in organic synthesis for the construction of more complex molecules in pharmaceutical and chemical research.

02 /Properties
Molecular weight136.15
Linear formulaH2NC6H4CONH2
Assay98%
Application4-Aminobenzamide was used as a poly(ADP-ribose)polymerase (PADPRP) inhhibitor to study the death of target cells by cytotoxic effector cells using the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP)1.
Melting point181-183 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H332Harmful if inhaled

Precautionary statements

  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)1
Hazard codes (EU)Xn
Risk statements (R)20/22-36/38
Safety statements (S)38

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
2835-68-9
MDL number
MFCD00007999
PubChem substance
24857167
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 4-Aminobenzamide used for?

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4-Aminobenzamide is primarily used as a poly(ADP-ribose)polymerase (PARP) inhibitor in biochemical and cellular research to study DNA repair and cell death mechanisms.

What are the CAS number and molecular formula for 4-Aminobenzamide?

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The CAS number for 4-Aminobenzamide is 2835-68-9, and its molecular formula is C <sub>7</sub>H <sub>8</sub>N <sub>2</sub>O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 4-Aminobenzamide with an assay of 98%. This product is suitable for research and chemical synthesis purposes. We do not represent it as USP, BP, or EP grade.

What are the safety considerations for handling 4-Aminobenzamide?

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4-Aminobenzamide is classified with GHS07 symbol and a 'Warning' signal word. It is harmful if swallowed (H302), causes skin irritation (H315), causes serious eye irritation (H319), and may cause respiratory irritation (H332). Appropriate personal protective equipment including a dust mask type N95, eyeshields, and gloves should be used. Handle in a well-ventilated area.

Does Tech Serve Solutions export 4-Aminobenzamide?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Aminobenzamide, serving customers worldwide.

How can I request a quote or sample for 4-Aminobenzamide?

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To request a quote or a sample of 4-Aminobenzamide, please contact our sales team through the website or call us directly. Our team will be happy to assist you with your requirements.

Need 4-Aminobenzamide in a specific grade or volume?