4-Amino-2-chloropyrimidine
4-Amino-2-chloropyrimidine (CAS: 7461-50-9), with the molecular formula C4H4ClN3 and a molecular weight of 129.55 g/mol, is a heterocyclic organic compound. It serves as a valuable building block in chemical synthesis, particularly within the realm of pharmaceutical research and development. Its structure, featuring a pyrimidine ring with amino and chloro substituents, makes it a versatile intermediate for creating more complex molecules.

Pharmaceutical Intermediate
This compound is frequently utilised as a key intermediate in the synthesis of active pharmaceutical ingredients (APIs). Its reactive sites allow for diverse chemical modifications essential for drug discovery and development pipelines.
Organic Synthesis Reagent
As a halogenated heterocycle, 4-Amino-2-chloropyrimidine is employed in various organic synthesis reactions. It facilitates the construction of novel chemical entities for research purposes across different scientific disciplines.
Heterocyclic Chemistry Research
Researchers in heterocyclic chemistry may use this compound to explore new reaction pathways and develop novel heterocyclic structures with potential applications in materials science and medicinal chemistry.
| Molecular weight | 129.55 |
|---|---|
| Empirical formula | C4H4ClN3 |
| Assay | 97% |
| Melting point | 197-205 °C |

Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-2-chloropyrimidine used for?
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4-Amino-2-chloropyrimidine is primarily used as a building block in chemical synthesis, particularly as an intermediate in the development of pharmaceuticals and other complex organic molecules. It is also utilised in heterocyclic chemistry research.
What is the CAS number and formula for 4-Amino-2-chloropyrimidine?
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The CAS number for 4-Amino-2-chloropyrimidine is 7461-50-9, and its molecular formula is C4H4ClN3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Amino-2-chloropyrimidine with a minimum assay of 97%. This product is intended for research and chemical synthesis purposes; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling requirements for 4-Amino-2-chloropyrimidine?
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This compound is classified as harmful if swallowed and causes serious eye irritation (H302, H319). Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, faceshields, and gloves. Ensure good ventilation and avoid dust formation. In case of eye contact, rinse cautiously with water for several minutes and seek medical advice.
How is 4-Amino-2-chloropyrimidine packed, shipped, and exported?
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Tech Serve Solutions professionally packs and ships chemicals globally, adhering to all necessary regulations for safe transport and export. Specific packaging details are available upon request.
How can I request a sample or quote for 4-Amino-2-chloropyrimidine?
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To request a sample or a quote for 4-Amino-2-chloropyrimidine, please contact our sales team through the website or via direct email, providing your specific requirements.
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