4-Amino-2-fluorobenzoic acid
4-Amino-2-fluorobenzoic acid (CAS: 446-31-1; Formula: H2NC6H3(F)CO2H) is a fluorinated aromatic amino acid derivative with a molecular weight of 155.13 g/mol. This compound serves as a valuable building block in organic synthesis. Its chemical structure, featuring both an amino group and a carboxylic acid group on a fluorinated benzene ring, makes it useful for creating more complex molecules, particularly in the fields of chemical biology and peptide chemistry.

Chemical Synthesis
Utilised as a key intermediate in the synthesis of diverse organic compounds. The presence of fluorine and reactive functional groups allows for targeted modifications in multi-step synthetic pathways.
Peptide Chemistry
Incorporated into peptide chains to create unnatural amino acid derivatives. This can modify the structural and functional properties of peptides for research purposes.
Chemical Biology Research
Serves as a reagent in studies exploring biological pathways and molecular interactions. Its unique structure can be employed to probe or develop novel biochemical tools.
| Molecular weight | 155.13 |
|---|---|
| Linear formula | H2NC6H3(F)CO2H |
| Assay | 97% |
| Melting point | 210 °C (dec.) |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-2-fluorobenzoic acid used for?
+
4-Amino-2-fluorobenzoic acid is primarily used as a building block in chemical synthesis, particularly for creating unnatural amino acid derivatives in peptide chemistry and for applications in chemical biology research.
What are the CAS number and formula for 4-Amino-2-fluorobenzoic acid?
+
The CAS number is 446-31-1 and the linear formula is H2NC6H3(F)CO2H.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 4-Amino-2-fluorobenzoic acid with an assay of 97%. We do not represent this product as meeting USP, BP, EP, or any other pharmacopoeia standards.
How should 4-Amino-2-fluorobenzoic acid be handled safely?
+
Handling requires a P261 (Avoid breathing dust), P280 (Wear protective gloves and eye protection), and P305 + P351 + P338 (IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing) approach. Use a dust mask type N95 (US), eye shields, and gloves. This compound is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation.
Is 4-Amino-2-fluorobenzoic acid a controlled substance?
+
The provided data does not indicate that 4-Amino-2-fluorobenzoic acid is a controlled substance.
How is 4-Amino-2-fluorobenzoic acid packed, shipped, and exported?
+
Tech Serve Solutions packs, ships, and exports chemicals in compliance with all relevant regulations for safe transport. Specific packaging details depend on quantity and destination.
How can I request a quote or sample for 4-Amino-2-fluorobenzoic acid?
+
To request a quote or sample, please contact our sales team through the website or by phone, providing your details and the product CAS number (446-31-1).
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis