4-Amino-2-chlorobenzoic acid
4-Amino-2-chlorobenzoic acid (CAS: 2457-76-3) is an aromatic amino acid derivative with the chemical formula H2NC6H3(Cl)CO2H and a molecular weight of 171.58 g/mol. This compound serves as a valuable building block in various chemical synthesis pathways, particularly within the fields of chemical biology and peptide chemistry. It is a key intermediate for the creation of more complex molecules and unnatural amino acid derivatives, contributing to advancements in research and development.

Chemical Synthesis Intermediate
Utilised as a fundamental building block in organic synthesis for the preparation of diverse chemical compounds. Its structure allows for further functionalization, enabling the construction of complex molecular architectures.
Peptide Chemistry
Incorporated into peptide synthesis for the development of modified peptides and peptidomimetics. It can introduce specific structural or functional properties into peptide chains.
Chemical Biology Research
Employed in research for probing biological systems and developing novel bioactive molecules. Its unique chemical features can be leveraged to study biological processes or design new therapeutic agents.
Unnatural Amino Acid Derivatives
Serves as a precursor for the synthesis of unnatural amino acids, expanding the scope of amino acid chemistry. These derivatives are crucial for creating peptides and proteins with novel functionalities.
| Molecular weight | 171.58 |
|---|---|
| Linear formula | H2NC6H3(Cl)CO2H |
| Assay | 97% |
| Melting point | 211 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Amino-2-chlorobenzoic acid primarily used for?
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4-Amino-2-chlorobenzoic acid is primarily used as an intermediate in chemical synthesis, particularly in peptide chemistry and the development of unnatural amino acid derivatives for chemical biology research.
What are the CAS number and chemical formula for 4-Amino-2-chlorobenzoic acid?
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The CAS number for 4-Amino-2-chlorobenzoic acid is 2457-76-3, and its chemical formula is H2NC6H3(Cl)CO2H.
What grade and purity does Tech Serve Solutions supply for 4-Amino-2-chlorobenzoic acid?
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Tech Serve Solutions supplies 4-Amino-2-chlorobenzoic acid with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the main safety hazards associated with 4-Amino-2-chlorobenzoic acid?
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4-Amino-2-chlorobenzoic acid is classified with the GHS07 symbol and a 'Warning' signal word. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335).
How should 4-Amino-2-chlorobenzoic acid be handled?
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When handling 4-Amino-2-chlorobenzoic acid, it is essential to wear appropriate personal protective equipment, including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. In case of contact with eyes, rinse cautiously with water for several minutes and remove contact lenses if present and easy to do.
How is 4-Amino-2-chlorobenzoic acid shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Amino-2-chlorobenzoic acid, adhering to all necessary regulations for safe and compliant international shipment.
How can I request a sample or quote for 4-Amino-2-chlorobenzoic acid?
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To request a sample or a quote for 4-Amino-2-chlorobenzoic acid, please contact our sales department through the website or by phone, providing your specific requirements.
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