4,6-Dimethoxyindole
4,6-Dimethoxyindole (CAS 23659-87-2) is a heterocyclic organic compound with the molecular formula C10H11NO2 and a molecular weight of 177.20 g/mol. This indole derivative serves as a key building block in chemical synthesis, particularly for creating complex molecules. Its primary applications lie in the preparation of various biologically active compounds, including potential therapeutic agents.
- Synonyms
- C10H11NO223659-87-2

Synthesis of HIV-1 Integrase Inhibitors
4,6-Dimethoxyindole is utilized as a reactant in the preparation of methoxy-substituted benzyl)indolebutenoic acids, which are investigated for their potential as HIV-1 integrase strand-transfer inhibitors.
Preparation of Antimitotic Agents
This compound functions as a precursor for synthesizing benzyl trimethoxyindole derivatives, which have been explored for their antimitotic properties.
Development of Antibacterial Agents
4,6-Dimethoxyindole is employed in the synthetic routes towards novel antibacterial compounds.
Synthesis of Anti-Tumor Agents
It serves as a building block for the preparation of pyridocarbazole and pyrrolocarbazole analogs with potential anti-tumor activity.
Human 5-HT6 Receptor Ligands
The compound is a reactant in the synthesis of methoxy-substituted N1-benzenesulfonylindole analogs, investigated as ligands for the human 5-HT6 serotonin receptor.
| Molecular weight | 177.20 |
|---|---|
| Empirical formula | C10H11NO2 |
| Assay | ≥98.0% (GC) |
| Application | • Reactant for preparation of methoxy-substituted (benzyl)indolebutenoic acids and their HIV-1 integrase strand-transfer inhibition1• Reactant for preparation of benzyl trimethoxyindoles as antimitotic agents2• Reactant for preparation of antibacterial agents3• Reactant for preparation of pyridocarbazoles and pyrrolocarbazole analogs as anti-tumor agents4• Reactant for preparation of methoxy-substituted N1-benzenesulfonylindole analogs as human 5-HT6 serotonin receptor ligands5 |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,6-Dimethoxyindole used for?
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4,6-Dimethoxyindole is primarily used as a reactant and building block in chemical synthesis for preparing various biologically active compounds, including potential HIV-1 integrase inhibitors, antimitotic agents, antibacterial agents, anti-tumor agents, and human 5-HT6 serotonin receptor ligands.
What are the CAS number and chemical formula for 4,6-Dimethoxyindole?
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The CAS number for 4,6-Dimethoxyindole is 23659-87-2, and its empirical formula (Hill notation) is C10H11NO2.
What grade and purity does Tech Serve Solutions supply for 4,6-Dimethoxyindole?
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Tech Serve Solutions supplies 4,6-Dimethoxyindole with a purity of ≥98.0% (GC). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for 4,6-Dimethoxyindole?
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4,6-Dimethoxyindole is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Recommended personal protective equipment includes a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust.
How is 4,6-Dimethoxyindole packed, shipped, and exported?
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4,6-Dimethoxyindole is available in various pack sizes suitable for laboratory and industrial use. Tech Serve Solutions is experienced in exporting fine chemicals globally, ensuring compliance with all relevant shipping regulations.
How can I request a sample or a quote for 4,6-Dimethoxyindole?
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To request a sample or a quote for 4,6-Dimethoxyindole, please contact our sales department through the website or by phone, providing your specific requirements.
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