4,6-Dimethoxysalicylaldehyde
4,6-Dimethoxysalicylaldehyde (CAS: 708-76-9) is an organic compound with the linear formula HOC₆H₂(OCH₃)₂CHO and a molecular weight of 182.17 g/mol. This aromatic aldehyde serves as a valuable building block in organic synthesis. Its structure makes it useful for preparing complex molecules, including ketocoumarin triplet sensitizers and natural product derivatives. It is supplied by Tech Serve Solutions with an assay of 98%.
- IUPAC
- 2,4-Dimethoxy-6-hydroxybenzaldehyde,4,6-Dimethoxy-2-hydroxybenzaldehyde
- Synonyms
- HOC6H2(OCH3)2CHO2,4-Dimethoxy-6-hydroxybenzaldehyde4,6-Dimethoxy-2-hydroxybenzaldehyde

Preparation of Ketocoumarin Sensitizers
4,6-Dimethoxysalicylaldehyde is utilized in the synthesis of novel ketocoumarin triplet sensitizers. These compounds exhibit efficiency in photochemical applications.
Total Synthesis of Natural Products
This chemical serves as a starting reagent in the total synthesis of complex natural products, such as the hexahydrodibenzofuran, (+/-)-linderol A.
Organic Synthesis Building Block
As an aromatic aldehyde with methoxy substituents, it acts as a versatile building block for constructing diverse organic molecules in research and development.
| Molecular weight | 182.17 |
|---|---|
| Linear formula | HOC6H2(OCH3)2CHO |
| Assay | 98% |
| Application | 4,6-Dimethoxysalicylaldehyde was used in the preparation of a new class of efficient ketocoumarin triplet sensitizers1. It was used as staring reagent in the total synthesis of (+/-)-linderol A, a hexahydrodibenzofuran2. |
| Melting point | 68-70 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,6-Dimethoxysalicylaldehyde used for?
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4,6-Dimethoxysalicylaldehyde is used as a building block in organic synthesis, notably for preparing ketocoumarin triplet sensitizers and in the total synthesis of natural products like (+/-)-linderol A.
What is the CAS number and formula for 4,6-Dimethoxysalicylaldehyde?
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The CAS number is 708-76-9, and its linear formula is HOC₆H₂(OCH₃)₂CHO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,6-Dimethoxysalicylaldehyde with an assay of 98%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for 4,6-Dimethoxysalicylaldehyde?
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This compound is a warning irritant (H315, H319, H335). Handle with appropriate personal protective equipment including a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation.
Is 4,6-Dimethoxysalicylaldehyde a controlled substance?
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The provided data does not indicate that 4,6-Dimethoxysalicylaldehyde is a controlled substance.
How can I request a quote or sample?
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To request a quote or sample, please contact our sales department through the website or by phone, referencing the product name and CAS number 708-76-9.
How is this chemical exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, adhering to all relevant regulations for international shipment.
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