4,5-Difluoro-2-methoxyphenylboronic acid
4,5-Difluoro-2-methoxyphenylboronic acid (CAS: 870777-32-5) is a fluorinated aryl boronic acid with the molecular formula C7H7BF2O3 and a molecular weight of 187.94 g/mol. This compound is primarily utilised as a building block in organic synthesis, particularly in cross-coupling reactions. Its specific substitution pattern makes it valuable for introducing fluorinated methoxyphenyl moieties into more complex molecules, finding applications in pharmaceutical and materials science research.
- Synonyms
- C7H7BF2O3870777-32-5
Organic Synthesis Intermediate
Serves as a key intermediate in the synthesis of complex organic molecules. It is particularly useful in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds.
Pharmaceutical Research
Employed in the development of novel pharmaceutical compounds where the incorporation of fluorinated aromatic rings is desired for modulating pharmacokinetic properties.
Materials Science
Utilised in the synthesis of advanced materials, such as organic light-emitting diodes (OLEDs) or specialised polymers, where its unique electronic and structural properties can be advantageous.
| Molecular weight | 187.94 |
|---|---|
| Empirical formula | C7H7BF2O3 |
| Application | Contains varying amounts of anhydride |
| Melting point | 175-180 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,5-Difluoro-2-methoxyphenylboronic acid used for?
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4,5-Difluoro-2-methoxyphenylboronic acid is primarily used as an intermediate in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions. It is also employed in pharmaceutical research and materials science for the introduction of fluorinated aromatic moieties.
What is the CAS number and molecular formula for this compound?
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The CAS number is 870777-32-5 and the molecular formula is C7H7BF2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific assay and grade are detailed in the product specifications. We do not represent this product as USP, BP, or EP grade.
How should 4,5-Difluoro-2-methoxyphenylboronic acid be handled safely?
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This compound is a Warning hazard, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area. Refer to the Safety Data Sheet for comprehensive handling instructions.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4,5-Difluoro-2-methoxyphenylboronic acid.
How can I request a sample or a quote?
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To request a sample or a quote for 4,5-Difluoro-2-methoxyphenylboronic acid, please contact our sales department through the website or by telephone.
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