4,5-Difluoro-2-nitrobenzoic acid
4,5-Difluoro-2-nitrobenzoic acid (CAS: 20372-63-8) is a fluorinated aromatic carboxylic acid with the linear formula F₂C₆H₂(NO₂)CO₂H and a molecular weight of 203.10 g/mol. This compound serves as a valuable building block in organic synthesis, particularly for the introduction of difluoronitrobenzoyl moieties. It is primarily utilized in research and development settings for the creation of novel molecules and advanced materials.
- Synonyms
- F2C6H2(NO2)CO2H

Organic Synthesis Intermediate
This compound functions as a key intermediate in multi-step organic syntheses. Its reactive carboxylic acid and nitro groups, along with the fluorinated phenyl ring, allow for diverse chemical transformations.
Building Block for Specialty Chemicals
4,5-Difluoro-2-nitrobenzoic acid is employed in the development of niche chemicals, including potential pharmaceutical intermediates and materials science precursors. The presence of fluorine atoms can impart unique properties to the target molecules.
Research and Development
The compound is supplied for laboratory use in academic and industrial research. It enables chemists to explore new synthetic pathways and develop innovative compounds with specific functionalities.
| Molecular weight | 203.10 |
|---|---|
| Linear formula | F2C6H2(NO2)CO2H |
| Assay | 99% |
| Melting point | 165-167 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4,5-Difluoro-2-nitrobenzoic acid used for?
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4,5-Difluoro-2-nitrobenzoic acid is primarily used as a building block and intermediate in organic synthesis for research and development purposes, including the creation of specialty chemicals and advanced materials.
What is the CAS number and formula for 4,5-Difluoro-2-nitrobenzoic acid?
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The CAS number is 20372-63-8, and the linear formula is F₂C₆H₂(NO₂)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4,5-Difluoro-2-nitrobenzoic acid with an assay of 99%. We do not represent this product as USP, BP, or EP grade.
How should 4,5-Difluoro-2-nitrobenzoic acid be handled safely?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation to prevent respiratory irritation (H335).
Does TSS export 4,5-Difluoro-2-nitrobenzoic acid?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals like 4,5-Difluoro-2-nitrobenzoic acid.
How can I request a quote or sample for 4,5-Difluoro-2-nitrobenzoic acid?
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Please contact our sales team via the website or your dedicated account manager to request a quote or sample.
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