4-(2-Tetrahydro-2H-pyranoxy)phenylmagnesium bromide solution
4-(2-Tetrahydro-2H-pyranoxy)phenylmagnesium bromide solution (CAS 36637-44-2) is an organometallic reagent, specifically a Grignard reagent, with the empirical formula C11H13BrMgO2 and a molecular weight of 281.43. It is supplied as a 0.5 M solution in Tetrahydrofuran (THF). This reactive compound is primarily utilised in organic synthesis as a versatile building block for introducing the 4-(2-Tetrahydro-2H-pyranoxy)phenyl moiety into target molecules.
Organic Synthesis Reagent
This Grignard reagent serves as a key intermediate in complex organic synthesis pathways. It is employed to form new carbon-carbon bonds by reacting with electrophiles such as aldehydes, ketones, esters, and epoxides.
Pharmaceutical Intermediate
The reagent's structure makes it valuable in the synthesis of advanced pharmaceutical intermediates. Its specific functionalisation allows for the precise construction of complex molecular architectures relevant to drug discovery and development.
Material Science Applications
In material science, this compound can be utilised in the synthesis of novel polymers or functionalised materials where the specific aromatic and protected hydroxyl group is required for desired properties.
| Molecular weight | 281.43 |
|---|---|
| Empirical formula | C11H13BrMgO2 |
| Boiling point | 65 °C |
| Density | 0.961 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2-Tetrahydro-2H-pyranoxy)phenylmagnesium bromide solution used for?
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This Grignard reagent is primarily used as a versatile building block in organic synthesis to introduce the 4-(2-Tetrahydro-2H-pyranoxy)phenyl group into target molecules, particularly in the development of pharmaceutical intermediates and complex organic compounds.
What is the CAS number and formula for this product?
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The CAS number is 36637-44-2 and the empirical formula (Hill notation) is C11H13BrMgO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical as a 0.5 M solution in THF. We do not represent it as USP, BP, EP, or any other pharmacopoeia grade unless explicitly stated. Purity is based on the specified molarity.
What are the primary safety concerns when handling this product?
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This product is a flammable liquid and vapour (H225), causes serious eye irritation (H319), and may cause respiratory irritation (H335). It is also suspected of causing cancer (H351). It can form explosive peroxides, requiring careful handling and storage away from light and air. Always follow appropriate safety protocols.
How is this chemical packed, shipped, and exported?
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This chemical is packed according to international shipping regulations for hazardous materials, classified under UN 2924. Tech Serve Solutions is a global supplier and exporter with extensive experience in handling and shipping fine chemicals worldwide.
How can I request a sample or obtain a quote?
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To request a sample or obtain a quote, please contact our sales department through the website or by calling our customer service line. Please reference the product name and CAS number (36637-44-2).
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