4-(2-Propynylcarbamoyl)phenylboronic acid pinacol ester
4-(2-Propynylcarbamoyl)phenylboronic acid pinacol ester (CAS: 1218790-49-8) is an organoboron compound with the molecular formula C16H20BNO3 and a molecular weight of 285.15 g/mol. This aryl boronate ester serves as a valuable building block in organic synthesis. Its structure, featuring a propargyl amide and a pinacol boronate ester moiety, makes it suitable for diverse cross-coupling reactions and the construction of complex molecules in pharmaceutical research and materials science.
- IUPAC
- N-(2-Propynyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide,[4-(Prop-2-ynylamine-1-carbonyl)phenyl]boronic acid pinacol ester
- Synonyms
- N-(2-Propynyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide[4-(Prop-2-ynylamine-1-carbonyl)phenyl]boronic acid pinacol ester
Organic Synthesis Reagent
Utilised as a versatile intermediate in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. The presence of both the boronate ester and the alkyne functional group allows for sequential or divergent synthetic strategies.
Pharmaceutical Research
Serves as a key building block in the synthesis of novel drug candidates and biologically active molecules. Its structure can be incorporated into diverse heterocyclic systems and pharmacophores.
Materials Science
Employed in the development of new organic materials, such as polymers and functional molecules, where the boronate ester can be involved in polymerisation or cross-linking processes.
| Molecular weight | 285.15 |
|---|---|
| Empirical formula | C16H20BNO3 |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2-Propynylcarbamoyl)phenylboronic acid pinacol ester used for?
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This compound is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the construction of complex molecules relevant to pharmaceutical research and materials science.
What is the CAS number and formula for 4-(2-Propynylcarbamoyl)phenylboronic acid pinacol ester?
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The CAS number is 1218790-49-8, and the molecular formula is C16H20BNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research and development purposes. The specific assay or purity is detailed in the product's Certificate of Analysis. It is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the safety and handling precautions for this chemical?
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This compound is classified as harmful if swallowed (H302). It requires handling with appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection such as a type N95 (US) or type P1 (EN143) respirator filter. Store in a well-ventilated area and avoid ingestion.
How is 4-(2-Propynylcarbamoyl)phenylboronic acid pinacol ester packed and shipped?
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Tech Serve Solutions packs and ships chemicals in compliance with international transport regulations for hazardous materials. Packaging is designed to ensure product integrity and safety during transit.
How can I request a sample or quote for this product?
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To request a sample or a quotation, please visit the product page on the Tech Serve Solutions website and use the designated enquiry form, or contact our sales team directly via email or phone.
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