O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate
O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate (CAS: 206752-41-2), with the empirical formula C17H24F6N5OP and a molecular weight of 459.37 g/mol, is a sophisticated uronium salt. It is primarily utilised as a coupling reagent in organic synthesis, particularly in peptide chemistry. Its effectiveness lies in facilitating amide bond formation, making it a valuable tool for researchers and synthetic chemists in academic and industrial laboratories.
- Synonyms
- N′-bis(pentamethylene)uronium hexafluorophosphate206752-41-2C17H24F6N5OP
Peptide Synthesis
This uronium salt acts as an efficient coupling reagent for the formation of peptide bonds. It facilitates the activation of carboxylic acids, enabling their reaction with amines to build peptide chains.
Organic Synthesis
Beyond peptide chemistry, it serves as a versatile reagent in general organic synthesis for constructing amide bonds in various complex molecules. Its application aids in the efficient creation of target compounds.
Chemical Biology Research
In chemical biology, it is employed to synthesise modified peptides or peptidomimetics. This enables the study of biological processes and the development of new therapeutic agents.
Reagent for Amidation
It is a key synthetic reagent for promoting the amidation reaction, crucial in the synthesis of pharmaceuticals and other fine chemicals.
| Molecular weight | 459.37 |
|---|---|
| Empirical formula | C17H24F6N5OP |
| Assay | 98% |
| Melting point | 206 °C (dec.)(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate used for?
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O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate is primarily used as a coupling reagent in organic synthesis, particularly for forming amide bonds in peptide chemistry and other complex molecular constructions.
What is the CAS number and molecular formula?
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The CAS number for O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate is 206752-41-2, and its empirical formula is C17H24F6N5OP.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate with an assay of 98%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate be handled?
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This compound is classified with GHS07 and a Warning signal word. It is harmful if swallowed, in contact with skin, or if inhaled, and causes skin and serious eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Adhere to precautionary statements P261, P280, and P305 + P351 + P338.
Is this product suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. This product can be shipped and exported internationally, subject to relevant regulations.
How can I request a sample or quote?
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To request a sample or a quote for O-Benzotriazol-1-yl-N,N,N′,N′-bis(pentamethylene)uronium hexafluorophosphate, please contact our sales team via the website or direct inquiry, providing your contact details and the quantity required.
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