O-Benzyl-L-serine
O-Benzyl-L-serine (CAS: 4726-96-9), with the molecular formula C10H13NO3 and a molecular weight of 195.22 g/mol, is a chiral amino acid derivative. It serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of complex molecules. Its specific stereochemistry makes it suitable for applications requiring enantiopure compounds, contributing to research in chemical biology and advanced material science.
- IUPAC
- (S)-2-Amino-3-benzyloxypropionic acid

Peptide Synthesis
O-Benzyl-L-serine is employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. The benzyl protecting group on the serine side chain can be removed under specific conditions, allowing for controlled peptide chain elongation.
Organic Synthesis Building Block
This compound acts as a versatile chiral synthon in the construction of various organic molecules. Its functional groups can be selectively modified to introduce complexity and specific stereochemistry into target compounds.
Chemical Biology Research
Researchers utilize O-Benzyl-L-serine in studies involving enzyme mechanisms, protein structure, and the synthesis of biologically active analogues. Its unique structure can help probe biological processes.
| Molecular weight | 195.22 |
|---|---|
| Empirical formula | C10H13NO3 |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D +21±2°, c = 2% in acetic acid: water (4:1) (+ 1 Eq HCl) |
| Optical purity | enantiomeric ratio: ≥99.5:0.5 (TLC) |
| Melting point | ~227 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-Benzyl-L-serine used for?
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O-Benzyl-L-serine is primarily used as a protected amino acid in peptide synthesis and as a chiral building block in organic synthesis for research in chemical biology and related fields.
What is the CAS number and molecular formula for O-Benzyl-L-serine?
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The CAS number is 4726-96-9, and the molecular formula is C10H13NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-Benzyl-L-serine with an assay of ≥99.0% (NT). We do not represent this product as meeting USP, BP, or EP pharmacopoeia standards.
How should O-Benzyl-L-serine be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. O-Benzyl-L-serine has a high-temperature melting point with decomposition.
Is O-Benzyl-L-serine a controlled substance?
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The provided data does not indicate that O-Benzyl-L-serine is a controlled substance.
How is O-Benzyl-L-serine packaged and exported?
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Tech Serve Solutions expertly handles the packaging and global export of fine chemicals, ensuring compliance with all relevant regulations for international shipment.
How can I request a sample or quote for O-Benzyl-L-serine?
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To request a sample or a quotation, please use the contact form on our website or reach out to our sales department directly.
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