O-Benzyl-DL-serine
O-Benzyl-DL-serine (CAS: 5445-44-3) is a protected amino acid derivative with the linear formula C6H5CH2OCH2CH(NH2)COOH and a molecular weight of 195.22 g/mol. It serves as a valuable building block in organic synthesis, particularly in peptide chemistry and chemical biology. This compound is essential for creating more complex molecules where selective protection of the serine side chain is required.
- IUPAC
- (±)-2-Amino-3-benzyloxypropionic acid

Peptide Synthesis
O-Benzyl-DL-serine is utilised as a protected amino acid in solid-phase or solution-phase peptide synthesis. The benzyl protecting group allows for controlled coupling reactions and subsequent deprotection under specific conditions.
Chemical Synthesis Intermediate
This compound acts as a key intermediate in the synthesis of various organic molecules. Its structure, featuring a protected hydroxyl group and an amino acid backbone, makes it versatile for constructing complex chemical entities.
Chemical Biology Research
Researchers in chemical biology may employ O-Benzyl-DL-serine for developing probes or modified biomolecules. Its incorporation can aid in studying biological processes or designing novel therapeutics.
| Molecular weight | 195.22 |
|---|---|
| Linear formula | C6H5CH2OCH2CH(NH2)COOH |
| Assay | ≥99.0% (NT) |
| Melting point | ~227 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-Benzyl-DL-serine used for?
+
O-Benzyl-DL-serine is primarily used as a protected amino acid in peptide synthesis, as an intermediate in chemical synthesis, and in chemical biology research for constructing complex molecules and modified biomolecules.
What are the CAS number and formula for O-Benzyl-DL-serine?
+
The CAS number for O-Benzyl-DL-serine is 5445-44-3. Its linear formula is C6H5CH2OCH2CH(NH2)COOH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies O-Benzyl-DL-serine with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should O-Benzyl-DL-serine be handled?
+
Handling O-Benzyl-DL-serine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. The compound has a high melting point and decomposes around 227 °C.
Is O-Benzyl-DL-serine a controlled substance?
+
The provided data does not indicate that O-Benzyl-DL-serine is a controlled substance.
How is O-Benzyl-DL-serine packed and exported?
+
Tech Serve Solutions, established in 1998, is a specialist global supplier and exporter of fine chemicals. Products are carefully packed and exported according to international regulations.
How can I request a quote or sample?
+
To request a quote or sample of O-Benzyl-DL-serine, please contact our sales team through the TSS website or designated contact channels.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis