4-(2-Keto-1-benzimidazolinyl)piperidine
4-(2-Keto-1-benzimidazolinyl)piperidine (CAS: 20662-53-7, C12H15N3O) is a heterocyclic organic compound with a molecular weight of 217.27 g/mol. It is primarily utilised as a building block in chemical synthesis, particularly in the development of pharmaceutical intermediates. Its structure lends itself to exploring structure-activity relationships in drug discovery, enabling the creation of potent and selective analogues for research purposes.

Pharmaceutical Intermediate Synthesis
This compound serves as a valuable intermediate in the synthesis of various pharmaceutical agents. Its unique benzimidazole and piperidine moieties allow for further functionalisation in the development of novel drug candidates.
Structure-Activity Relationship Studies
As documented, 4-(2-Keto-1-benzimidazolinyl)piperidine has been employed in research to investigate structure-activity relationships. This involves synthesising potent and selective analogues to understand how structural modifications impact biological activity.
Organic Synthesis Building Block
This chemical acts as a versatile building block in organic synthesis. Its heterocyclic nature makes it suitable for incorporation into complex molecular architectures across various research and development fields.
| Molecular weight | 217.27 |
|---|---|
| Empirical formula | C12H15N3O |
| Assay | 98% |
| Application | 4-(2-Keto-1-benzimidazolinyl)piperidine was used to study the structure–activity relationships with several potent and selective analogues1. |
| Melting point | 183-185 °C(lit.) |

Hazard statements
- H301Toxic if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25-36/37/38 |
| Safety statements (S) | 26-36-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-(2-Keto-1-benzimidazolinyl)piperidine used for?
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4-(2-Keto-1-benzimidazolinyl)piperidine is used as a building block in chemical synthesis, particularly for studying structure-activity relationships and developing pharmaceutical intermediates.
What is the CAS number and formula for 4-(2-Keto-1-benzimidazolinyl)piperidine?
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The CAS number is 20662-53-7, and the empirical formula is C12H15N3O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should 4-(2-Keto-1-benzimidazolinyl)piperidine be handled safely?
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This compound is classified as toxic if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Handle with appropriate personal protective equipment, including eyeshields, faceshields, gloves, and a P2 respirator. Avoid breathing dust/fume/gas/mist/vapours/spray.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-(2-Keto-1-benzimidazolinyl)piperidine.
How can I request a sample or quote?
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To request a sample or a quote for 4-(2-Keto-1-benzimidazolinyl)piperidine, please contact our sales team through the website or by phone.
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