3-(Trimethylsilyl)propargyl alcohol
3-(Trimethylsilyl)propargyl alcohol (CAS 5272-36-6) is a versatile organic compound with the linear formula (CH3)3SiC≡CCH2OH and a molecular weight of 128.24 g/mol. It functions as a valuable building block in organic synthesis. Its unique structure, featuring both a silyl group and a propargyl alcohol moiety, enables its participation in various chemical transformations for creating complex molecules.
- IUPAC
- 3-(Trimethylsilyl)-2-propyn-1-ol
- Synonyms
- 3-(Trimethylsilyl)-2-propyn-1-ol

Organic Synthesis Intermediate
This compound serves as a key intermediate in the synthesis of complex organic molecules, particularly those requiring the introduction of a propargyl alcohol or a trimethylsilyl-protected alkyne unit.
Building Block for Novel Compounds
Its bifunctional nature makes it an excellent building block for constructing novel pharmaceuticals, agrochemicals, and advanced materials, facilitating diverse synthetic routes.
Research and Development
Utilised extensively in academic and industrial research laboratories for exploring new synthetic methodologies and developing innovative chemical entities.
| Molecular weight | 128.24 |
|---|---|
| Linear formula | (CH3)3SiC≡CCH2OH |
| Assay | 99% |
| Boiling point | 76 °C/11 mmHg(lit.) |
| Density | 0.865 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.451(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 67 °C / 152.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trimethylsilyl)propargyl alcohol used for?
+
3-(Trimethylsilyl)propargyl alcohol is primarily used as an intermediate and building block in organic synthesis for the creation of complex molecules and novel chemical entities.
What is the CAS number and formula for 3-(Trimethylsilyl)propargyl alcohol?
+
The CAS number is 5272-36-6 and the linear formula is (CH3)3SiC≡CCH2OH.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-(Trimethylsilyl)propargyl alcohol with an assay of 99%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(Trimethylsilyl)propargyl alcohol be handled safely?
+
Handling requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. It has a flash point of 67°C (152.6°F) and is classified under WGK Germany 3, indicating it is hazardous to water.
Is 3-(Trimethylsilyl)propargyl alcohol a controlled substance?
+
Based on the provided data, there is no indication that 3-(Trimethylsilyl)propargyl alcohol is a controlled substance.
How is 3-(Trimethylsilyl)propargyl alcohol packed, shipped, and exported?
+
Tech Serve Solutions expertly packs, ships, and exports fine chemicals globally, adhering to all necessary regulations to ensure safe and compliant delivery.
How can I request a quote or sample for 3-(Trimethylsilyl)propargyl alcohol?
+
Please contact our sales team via our website or directly by phone to request a quote or a sample of 3-(Trimethylsilyl)propargyl alcohol.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis