3-(Trifluoromethyl)phenyl isothiocyanate
3-(Trifluoromethyl)phenyl isothiocyanate (CAS: 1840-19-3; Formula: CF3C6H4NCS; Molar Mass: 203.18 g/mol) is a valuable organic building block and sulfur compound. It is an isothiocyanate derivative featuring a trifluoromethyl group on a phenyl ring. This compound serves as a key intermediate in chemical synthesis, particularly for the creation of complex organic molecules, heterocycles, and potential pharmaceutical candidates. Its unique functional groups offer diverse reactivity for further chemical transformations.
Organic Synthesis Intermediate
Utilised as a building block in the synthesis of various organic compounds. Its isothiocyanate group readily reacts with nucleophiles, making it useful for constructing nitrogen- and sulfur-containing heterocycles.
Pharmaceutical Research
Serves as a precursor in the development of novel chemical entities with potential biological activity. It is employed in the synthesis of molecules investigated for therapeutic applications.
Agrochemical Development
Can be incorporated into the synthesis pathways of new agrochemicals, leveraging its structural features for targeted biological effects.
| Molecular weight | 203.18 |
|---|---|
| Linear formula | CF3C6H4NCS |
| Assay | 98% |
| Boiling point | 206-208 °C(lit.) |
| Density | 1.335 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5547(lit.) |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 95 °C / 203 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)phenyl isothiocyanate used for?
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3-(Trifluoromethyl)phenyl isothiocyanate is primarily used as a versatile intermediate in organic synthesis, including the development of pharmaceutical and agrochemical compounds. It is a valuable building block for creating nitrogen- and sulfur-containing heterocycles.
What are the CAS number and formula for 3-(Trifluoromethyl)phenyl isothiocyanate?
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The CAS number is 1840-19-3 and the molecular formula is CF3C6H4NCS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)phenyl isothiocyanate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should 3-(Trifluoromethyl)phenyl isothiocyanate be handled safely?
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This compound is classified as Danger, with hazards including H302, H312, H314, H332, and H335. It is corrosive and harmful if swallowed, in contact with skin, or inhaled. Appropriate personal protective equipment, including gloves, goggles, and respiratory protection (type ABEK filter or equivalent), must be used. Handle only in a well-ventilated area or fume hood. In case of contact, follow the recommended safety statements.
Is 3-(Trifluoromethyl)phenyl isothiocyanate controlled or scheduled?
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The provided data does not indicate that 3-(Trifluoromethyl)phenyl isothiocyanate is a controlled or scheduled substance.
How is 3-(Trifluoromethyl)phenyl isothiocyanate packed, shipped, and exported?
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As a specialist global supplier, Tech Serve Solutions packages and exports chemicals like 3-(Trifluoromethyl)phenyl isothiocyanate in compliance with all relevant international shipping regulations to ensure safe and secure delivery worldwide.
How can I request a quote or sample for 3-(Trifluoromethyl)phenyl isothiocyanate?
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To request a quote or sample for 3-(Trifluoromethyl)phenyl isothiocyanate, please contact our sales team through the website or by phone. Specify the product name and CAS number (1840-19-3) in your inquiry.
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