3-(Trifluoromethyl)phenyl chloroformate
3-(Trifluoromethyl)phenyl chloroformate (CAS: 95668-29-4) is a reactive organic compound with the linear formula ClCO<sub>2</sub>C<sub>6</sub>H<sub>4</sub>CF<sub>3</sub> and a molecular weight of 224.56 g/mol. As an acid halide and carbonyl compound, it serves as a versatile building block in organic synthesis. Its primary applications lie in the preparation of various chemical intermediates and specialized organic molecules for research and development purposes.
Reagent in Organic Synthesis
This chloroformate acts as a derivatizing agent and a precursor for introducing the 3-(trifluoromethyl)phenoxycarbonyl group into organic molecules. It is valuable for creating esters and carbamates in multi-step syntheses.
Pharmaceutical Intermediate Synthesis
The compound is utilized in the synthesis pathways for developing new pharmaceutical candidates. Its trifluoromethylphenyl moiety can impart specific pharmacokinetic properties to drug molecules.
Agrochemical Research
It may be employed in the research and development of novel agrochemicals, where the trifluoromethyl group is often associated with enhanced biological activity.
Material Science Applications
Potential uses include the modification of polymers or the synthesis of specialized monomers where its unique structural features are beneficial.
| Molecular weight | 224.56 |
|---|---|
| Linear formula | ClCO2C6H4CF3 |
| Assay | 95% |
| Vapour pressure | 1.09 psi (20 °C) |
| Storage temperature | 2-8°C |
Hazard statements
- H301Toxic if swallowed
- H311Toxic in contact with skin
- H314Causes severe skin burns and eye damage
- H331Toxic if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 85 °C / 185 °F |
| Transport (UN / ADR) | UN 3277 6.1/PG 2 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 23/24/25-34 |
| Safety statements (S) | 23-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)phenyl chloroformate used for?
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3-(Trifluoromethyl)phenyl chloroformate is primarily used as a reagent in organic synthesis, particularly for introducing the 3-(trifluoromethyl)phenoxycarbonyl group to form esters and carbamates. It serves as a building block in the synthesis of pharmaceutical intermediates, agrochemicals, and potentially in material science research.
What is the CAS number and formula for 3-(Trifluoromethyl)phenyl chloroformate?
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The CAS number for 3-(Trifluoromethyl)phenyl chloroformate is 95668-29-4. Its linear formula is ClCO<sub>2</sub>C<sub>6</sub>H<sub>4</sub>CF<sub>3</sub>.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)phenyl chloroformate with a minimum assay of 95%. This product is suitable for research and synthesis purposes. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-(Trifluoromethyl)phenyl chloroformate be handled safely?
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3-(Trifluoromethyl)phenyl chloroformate is a corrosive and toxic substance. Handling requires strict safety protocols, including the use of full-face respirators, chemical-resistant gloves, and eye protection (goggles and face shield). Ensure adequate ventilation and avoid inhalation, skin, and eye contact. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
How is 3-(Trifluoromethyl)phenyl chloroformate packed and shipped?
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Tech Serve Solutions packages and exports 3-(Trifluoromethyl)phenyl chloroformate in compliance with international shipping regulations for hazardous materials. Specific packaging details can be provided upon request.
How can I request a quote or sample?
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To request a quote or a sample of 3-(Trifluoromethyl)phenyl chloroformate, please visit the Tech Serve Solutions website or contact our sales department directly with your inquiry.
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