3-(Trifluoromethyl)-L-phenylalanine
3-(Trifluoromethyl)-L-phenylalanine (CAS: 14464-68-7), with the molecular formula C10H10F3NO2 and a molecular weight of 233.19 g/mol, is a key unnatural amino acid derivative. It is widely employed in chemical biology and peptide chemistry for its unique trifluoromethyl substitution, which can significantly alter the properties of peptides and proteins. This compound serves as a valuable building block in complex chemical synthesis.
- IUPAC
- (S)-2-Amino-3-[3-(trifluoromethyl)phenyl]propionic acid
Chemical Biology Research
Utilised in biochemical studies to probe protein structure-function relationships and develop novel biological probes. Its trifluoromethyl group can enhance metabolic stability or act as a spectroscopic tag.
Peptide Synthesis
Incorporated into synthetic peptides to modify their conformational preferences, binding affinities, or pharmacokinetic profiles. This enables the creation of peptides with tailored biological activities.
Drug Discovery and Development
Serves as a scaffold or intermediate in the synthesis of potential pharmaceutical agents. The trifluoromethyl moiety can improve lipophilicity and cell permeability of drug candidates.
Organic Synthesis Intermediate
A versatile building block for constructing complex organic molecules, leveraging the reactivity of the amino acid and the influence of the trifluoromethylphenyl group.
| Molecular weight | 233.19 |
|---|---|
| Empirical formula | C10H10F3NO2 |
| Assay | ≥96% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)-L-phenylalanine used for?
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3-(Trifluoromethyl)-L-phenylalanine is used in chemical biology, peptide chemistry, and as an intermediate in chemical synthesis, particularly for developing novel peptides and pharmaceutical agents.
What is the CAS number and formula for 3-(Trifluoromethyl)-L-phenylalanine?
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The CAS number is 14464-68-7 and the empirical formula (Hill notation) is C10H10F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)-L-phenylalanine with an assay of ≥96% (HPLC). We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling recommendations for this compound?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used. This compound is classified under WGK Germany 3, indicating a high hazard to water.
How is 3-(Trifluoromethyl)-L-phenylalanine packed, shipped, and exported?
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Tech Serve Solutions offers reliable global supply and export of 3-(Trifluoromethyl)-L-phenylalanine, ensuring secure packaging suitable for international transport.
How can I request a sample or quote for 3-(Trifluoromethyl)-L-phenylalanine?
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To request a sample or a quotation, please contact our sales team through the website or by calling our office.
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