3-(Trifluoromethyl)-D-phenylalanine
3-(Trifluoromethyl)-D-phenylalanine (CAS: 14464-67-6) is a chiral, unnatural amino acid derivative with the molecular formula C10H10F3NO2 and a molecular weight of 233.19 g/mol. This compound is an important building block in medicinal chemistry and chemical synthesis, particularly for the development of novel peptide analogues and pharmaceutical agents. Its unique trifluoromethyl group imparts specific physicochemical properties valuable in drug design.
- IUPAC
- (R)-2-Amino-3-[3-(trifluoromethyl)phenyl]propionic acid
Peptide Synthesis
Incorporated into peptide chains to modify properties such as metabolic stability, lipophilicity, and binding affinity. Serves as a non-canonical amino acid in the construction of peptidomimetics.
Medicinal Chemistry
Utilised as a key intermediate in the synthesis of biologically active molecules and pharmaceutical candidates. The trifluoromethyl moiety can enhance drug efficacy and pharmacokinetic profiles.
Chemical Biology Research
Employed in the design and synthesis of probes for biological studies. Aids in understanding protein-ligand interactions and enzyme mechanisms.
Asymmetric Synthesis
Acts as a chiral building block in complex organic syntheses, contributing stereochemical control to target molecules.
| Molecular weight | 233.19 |
|---|---|
| Empirical formula | C10H10F3NO2 |
| Assay | ≥96.0% (HPLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)-D-phenylalanine used for?
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This compound is primarily used in peptide synthesis, medicinal chemistry, chemical biology research, and asymmetric synthesis as a specialised building block.
What is the CAS number and molecular formula for 3-(Trifluoromethyl)-D-phenylalanine?
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The CAS number is 14464-67-6 and the molecular formula is C10H10F3NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-(Trifluoromethyl)-D-phenylalanine with an assay of ≥96.0% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 3-(Trifluoromethyl)-D-phenylalanine be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK classification of 3 in Germany, indicating high hazard.
How is this chemical shipped?
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Tech Serve Solutions exports fine chemicals globally, adhering to all necessary regulations for safe and compliant transport.
How can I request a sample or quote for 3-(Trifluoromethyl)-D-phenylalanine?
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Please contact our sales team via the website or direct email to request a sample or a quotation for your specific requirements.
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