3-(Trifluoromethyl)aniline
3-(Trifluoromethyl)aniline (CAS: 98-16-8), with the molecular formula CF3C6H4NH2 and a molecular weight of 161.12 g/mol, is a crucial aromatic amine intermediate. It is widely employed in the synthesis of pharmaceuticals, agrochemicals, and dyes. This compound serves as a fundamental building block in organic chemistry, enabling the introduction of the trifluoromethylphenyl moiety into complex molecular structures.
- IUPAC
- α,α,α-Trifluoro-m-toluidine,3-Aminobenzotrifluoride
- Synonyms
- α,α,α-Trifluoro-m-toluidine3-Aminobenzotrifluoride
Pharmaceutical Synthesis
3-(Trifluoromethyl)aniline is a key intermediate in the synthesis of various active pharmaceutical ingredients (APIs). Its unique structure allows for the development of novel therapeutic agents across different medical fields.
Agrochemical Development
This compound is utilized in the creation of modern pesticides, herbicides, and fungicides. The trifluoromethyl group often enhances the biological activity and stability of agrochemical products.
Dye and Pigment Manufacturing
It serves as a precursor in the production of specialized dyes and pigments, contributing to vibrant colours and enhanced chemical resistance in finished products.
Organic Building Block
As a versatile building block, 3-(Trifluoromethyl)aniline is essential for academic and industrial research in organic synthesis, facilitating the construction of complex organic molecules.
| Molecular weight | 161.12 |
|---|---|
| Linear formula | CF3C6H4NH2 |
| Assay | ≥99% |
| Boiling point | 187 °C(lit.) |
| Density | 1.29 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.480(lit.) |
| Vapour pressure | 0.3 mmHg (20 °C) |
| Melting point | 5-6 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H330Fatal if inhaled
- H373May cause damage to organs through prolonged exposure
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 87 °C / 188.6 °F |
| Transport (UN / ADR) | UN 2948 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 22-24-26-33 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(Trifluoromethyl)aniline used for?
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3-(Trifluoromethyl)aniline is primarily used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and as a general building block in organic chemistry.
What are the CAS number and chemical formula for 3-(Trifluoromethyl)aniline?
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The CAS number for 3-(Trifluoromethyl)aniline is 98-16-8 and its chemical formula is CF3C6H4NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies 3-(Trifluoromethyl)aniline with an assay of ≥99%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 3-(Trifluoromethyl)aniline be handled safely?
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3-(Trifluoromethyl)aniline is a dangerous substance. Handle with extreme caution, using appropriate personal protective equipment including eyeshields, faceshields, gloves, and a suitable respirator. Avoid inhalation, ingestion, and skin contact. Refer to the safety data sheet for detailed handling instructions.
Is 3-(Trifluoromethyl)aniline exported or shipped by TSS?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-(Trifluoromethyl)aniline.
How can I request a quote or sample of 3-(Trifluoromethyl)aniline?
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Please contact our sales department through the website or by phone to request a quote or sample of 3-(Trifluoromethyl)aniline.
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