3-(N,N-Dimethyloctadecylammonio)propanesulfonate
3-(N,N-Dimethyloctadecylammonio)propanesulfonate (CAS: 13177-41-8) is a zwitterionic surfactant with the linear formula CH3(CH2)17N+(CH3)2CH2CH2CH2SO3-. This compound, also known as Stearyl sulfobetaine, is primarily utilised in specialised biochemical applications. Its key advantage lies in its UV transparency, making it ideal for spectrophotometric analysis of proteins, particularly in membrane solubilisation studies.
- IUPAC
- 3-(N,N-Dimethylstearylammonio)propanesulfonate,3-(Stearyl-dimethylammonio)propanesulfonate,N-Octadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate,SB3-18,Stearyl sulfobetaine
- Synonyms
- Stearyl sulfobetaineSB3-183-(Dimethylstearylammonio)propanesulfonate3-(Stearyl-dimethylammonio)propanesulfonateN-Octadecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate

Membrane Protein Solubilization
This zwitterionic surfactant is particularly effective for solubilising membrane proteins. Its unique properties allow for the extraction and study of these complex biological molecules without interfering with subsequent spectrophotometric analysis.
Spectrophotometric Analysis
Due to its lack of UV absorbance, 3-(N,N-Dimethyloctadecylammonio)propanesulfonate is an excellent choice for studies involving proteins. It ensures that analytical measurements are not confounded by the presence of the surfactant itself.
Biochemical Research Reagent
As a biochemical and reagent, it serves as a valuable tool in various research settings. Its amphipathic nature makes it useful for applications requiring surface activity and mild solubilisation properties.
| Molecular weight | 419.71 |
|---|---|
| Linear formula | CH3(CH2)17N+(CH3)2CH2CH2CH2SO3- |
| Assay | ≥99.0% (TLC) |
| Application | Zwitterionic surfactant useful in membrane solubilization studies. Does not absorb UV light and hence does not interfere with spectrophotometric analysis of proteins.1 |
| Melting point | 257-260 °C (dec.)(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Description | zwitterionic |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(N,N-Dimethyloctadecylammonio)propanesulfonate used for?
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3-(N,N-Dimethyloctadecylammonio)propanesulfonate (CAS: 13177-41-8) is a zwitterionic surfactant useful in membrane solubilization studies. Its UV transparency makes it suitable for spectrophotometric analysis of proteins.
What are the CAS number and formula for 3-(N,N-Dimethyloctadecylammonio)propanesulfonate?
+
The CAS number is 13177-41-8. The linear formula is CH3(CH2)17N+(CH3)2CH2CH2CH2SO3-.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥99.0% (TLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
What are the main safety hazards associated with this chemical?
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This compound is classified as a Warning. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific packing and shipping details are available upon request, adhering to international regulations for chemical export.
How can I request a sample or obtain a quote for this product?
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You can request a sample or obtain a quote by contacting our sales team directly through our website or by calling our customer service line. Please reference the product name and CAS number.
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