4-O-Acetyl-3,6-di-O-(tert-butyldimethylsilyl)-D-glucal
4-O-Acetyl-3,6-di-O-(tert-butyldimethylsilyl)-D-glucal (CAS: 132891-79-3) is a complex carbohydrate derivative with a molecular weight of 416.70 g/mol. This silane-protected glucal serves as a valuable intermediate in organic synthesis, particularly for constructing complex glycosylated molecules. Its protected hydroxyl groups allow for regioselective modifications, making it a key building block in carbohydrate chemistry and related fields.
- Synonyms
- 4-O-Acetyl-3,6-di-O-TBDMS-D-glucal

Glycosylation Reactions
Utilised as a glycosyl donor in the synthesis of various oligosaccharides and glycoconjugates. The protected nature of the hydroxyl groups allows for controlled stereochemistry during glycosidic bond formation.
Synthesis of Complex Carbohydrates
A crucial building block for the construction of structurally complex carbohydrates, including natural products and modified sugars. Its protected functional groups enable selective chemical transformations.
Chemical Biology Research
Employed in research settings for the synthesis of carbohydrate-based probes and analogues for studying biological processes and interactions. Its structure allows for further functionalization.
Pharmaceutical Intermediate
Serves as a precursor or intermediate in the multi-step synthesis of pharmaceutical compounds where a specific carbohydrate moiety is required.
| Molecular weight | 416.70 |
|---|---|
| Empirical formula | C20H40O5Si2 |
| Boiling point | 324 °C(lit.) |
| Density | 0.968 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.456(lit.) |
| Flash point | >113 °C / >235.4 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-O-Acetyl-3,6-di-O-(tert-butyldimethylsilyl)-D-glucal used for?
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This compound is primarily used as an intermediate in organic synthesis, particularly in carbohydrate chemistry for constructing complex oligosaccharides, glycoconjugates, and pharmaceutical compounds.
What are the CAS number and formula for this compound?
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The CAS number is 132891-79-3, and its empirical formula is C20H40O5Si2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research and development purposes. The specific grade and purity are available upon request, and it is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should 4-O-Acetyl-3,6-di-O-(tert-butyldimethylsilyl)-D-glucal be handled?
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As a chemical substance, it should be handled with appropriate personal protective equipment (gloves, eye protection) in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for detailed handling and hazard information.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and can arrange shipment worldwide, subject to relevant regulations.
How can I request a sample or quote for this product?
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Samples and quotes can be requested through the Tech Serve Solutions website or by contacting our sales department directly.
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