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3-(N-Boc-amino)phenylboronic acid

CAS 380430-68-2(CH3)3CO2CNHC6H4B(OH)2Chemical Synthesis

3-(N-Boc-amino)phenylboronic acid (CAS: 380430-68-2) is a protected aryl boronic acid derivative with a molecular weight of 237.06 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its applications include participation in rhodium-catalyzed and palladium-catalyzed coupling chemistries, facilitating the formation of new carbon-carbon bonds in complex molecule construction.

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3-(N-Boc-amino)phenylboronic acid ((CH3)3CO2CNHC6H4B(OH)2) — chemical structure, CAS 380430-68-2; Chemistry, fine chemical supplied by Tech Serve Solutions
Aryl Boronic AcidsBoronic AcidsChemical Synthesis
01 /Applications

Suzuki-Miyaura Coupling Reagent

Utilised as a key reactant in palladium-catalyzed Suzuki-Miyaura coupling reactions, enabling the synthesis of biaryl compounds and other complex organic structures.

Rhodium-Catalyzed Cross-Coupling

Functions as a substrate in rhodium-catalyzed cross-coupling processes, offering an alternative route for carbon-carbon bond formation in synthetic chemistry.

Organic Synthesis Intermediate

Serves as a versatile intermediate in the construction of sophisticated organic molecules, particularly where an aminophenylboronic acid moiety is required.

02 /Properties
Molecular weight237.06
Linear formula(CH3)3CO2CNHC6H4B(OH)2
Assay≥95%
ApplicationReactant for:• Rhodium-catalyzed cross-coupling1• Pd-catalyzed Suzuki-Miyaura coupling2,3
Melting point168 °C (dec.)(lit.)
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
380430-68-2
MDL number
MFCD03411945
PubChem substance
24880955
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-(N-Boc-amino)phenylboronic acid used for?

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3-(N-Boc-amino)phenylboronic acid is primarily used as a reactant in rhodium-catalyzed and palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the synthesis of complex organic molecules.

What is the CAS number and molecular formula for this compound?

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The CAS number is 380430-68-2. The linear formula is (CH3)3CO2CNHC6H4B(OH)2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound with an assay of ≥95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.

What are the safety and handling considerations for this chemical?

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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a melting point of approximately 168 °C with decomposition and is classified under WGK Germany 3.

Can Tech Serve Solutions export this chemical?

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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can arrange shipment worldwide.

How can I request a sample or quote for 3-(N-Boc-amino)phenylboronic acid?

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Please contact our sales team directly via phone or email to request a sample or obtain a quotation for this product.

Need 3-(N-Boc-amino)phenylboronic acid in a specific grade or volume?