3-(N-Boc-amino)phenylboronic acid
3-(N-Boc-amino)phenylboronic acid (CAS: 380430-68-2) is a protected aryl boronic acid derivative with a molecular weight of 237.06 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in cross-coupling reactions. Its applications include participation in rhodium-catalyzed and palladium-catalyzed coupling chemistries, facilitating the formation of new carbon-carbon bonds in complex molecule construction.

Suzuki-Miyaura Coupling Reagent
Utilised as a key reactant in palladium-catalyzed Suzuki-Miyaura coupling reactions, enabling the synthesis of biaryl compounds and other complex organic structures.
Rhodium-Catalyzed Cross-Coupling
Functions as a substrate in rhodium-catalyzed cross-coupling processes, offering an alternative route for carbon-carbon bond formation in synthetic chemistry.
Organic Synthesis Intermediate
Serves as a versatile intermediate in the construction of sophisticated organic molecules, particularly where an aminophenylboronic acid moiety is required.
| Molecular weight | 237.06 |
|---|---|
| Linear formula | (CH3)3CO2CNHC6H4B(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:• Rhodium-catalyzed cross-coupling1• Pd-catalyzed Suzuki-Miyaura coupling2,3 |
| Melting point | 168 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(N-Boc-amino)phenylboronic acid used for?
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3-(N-Boc-amino)phenylboronic acid is primarily used as a reactant in rhodium-catalyzed and palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura coupling, for the synthesis of complex organic molecules.
What is the CAS number and molecular formula for this compound?
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The CAS number is 380430-68-2. The linear formula is (CH3)3CO2CNHC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥95%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling considerations for this chemical?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a melting point of approximately 168 °C with decomposition and is classified under WGK Germany 3.
Can Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and can arrange shipment worldwide.
How can I request a sample or quote for 3-(N-Boc-amino)phenylboronic acid?
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Please contact our sales team directly via phone or email to request a sample or obtain a quotation for this product.
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