Hoveyda-Grubbs Catalyst 2nd Generation
Hoveyda-Grubbs Catalyst 2nd Generation (CAS: 301224-40-8; Formula: C31H38Cl2N2ORu; MW: 626.62) is a sophisticated ruthenium-based catalyst essential for olefin metathesis reactions. It is highly efficient in catalysing ring-closing, ring-opening, and cross-metathesis processes, particularly with challenging, electron-deficient substrates. This catalyst is widely employed in chemical synthesis, polymer science, and materials science for constructing complex organic molecules and polymers.
- IUPAC
- (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium
Olefin Metathesis
Hoveyda-Grubbs Catalyst 2nd Generation is a key reagent for catalyzing various olefin metathesis reactions, including ring-closing, ring-opening, and cross-metathesis. Its efficacy extends to the transformation of sterically hindered and electron-deficient olefins, which are often difficult to functionalise with other metathesis catalysts.
Polymer Synthesis
This catalyst is instrumental in the synthesis of polymers via ring-opening metathesis polymerisation (ROMP). It enables the controlled polymerisation of cyclic olefins, leading to materials with tailored properties for diverse applications in materials science.
Complex Organic Synthesis
Its high reactivity and functional group tolerance make Hoveyda-Grubbs Catalyst 2nd Generation a valuable tool in the synthesis of complex organic molecules. It facilitates the formation of carbon-carbon double bonds, crucial for building intricate molecular architectures in pharmaceuticals and fine chemicals.
| Molecular weight | 626.62 |
|---|---|
| Empirical formula | C31H38Cl2N2ORu |
| Assay | 97% |
| Storage temperature | 2-8°C |
| Application | Metathesis: Ruthenium-Based Metathesis CatalystsMetathesis catalyst with efficiencies similar to Grubbs Catalyst 2nd generation but with different substrate specificity. Catalyzes ring-closing, ring-opening,12,13 and cross-metathesis reactions of highly electron-deficient substrates.14,15 |
| Melting point | 216-220 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Hoveyda-Grubbs Catalyst 2nd Generation used for?
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Hoveyda-Grubbs Catalyst 2nd Generation is primarily used for olefin metathesis reactions, including ring-closing, ring-opening, and cross-metathesis. It is particularly effective with electron-deficient substrates and in polymer synthesis via ring-opening metathesis polymerisation.
What are the CAS number and formula for Hoveyda-Grubbs Catalyst 2nd Generation?
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The CAS number is 301224-40-8, and the empirical formula is C31H38Cl2N2ORu.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Hoveyda-Grubbs Catalyst 2nd Generation with an assay of 97%. It is supplied as a research or technical grade material and is not represented as USP, BP, or EP grade.
How should Hoveyda-Grubbs Catalyst 2nd Generation be handled and stored?
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This catalyst requires specific handling procedures. Personal protective equipment, including eyeshields and gloves, should be worn. In situations with potential for airborne exposure, a type N95 (US) or type P1 (EN143) respirator filter is recommended. Store at 2-8°C.
Is Hoveyda-Grubbs Catalyst 2nd Generation a controlled substance?
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The provided data does not indicate that Hoveyda-Grubbs Catalyst 2nd Generation is a controlled substance. Please consult local regulations for specific import and handling requirements.
How can I request a quote or sample for Hoveyda-Grubbs Catalyst 2nd Generation?
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To request a quote or sample, please contact our sales team via the website or by phone. We are happy to assist with your specific requirements for this chemical.
How is Hoveyda-Grubbs Catalyst 2nd Generation packed, shipped, and exported?
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Tech Serve Solutions packs, ships, and exports Hoveyda-Grubbs Catalyst 2nd Generation in compliance with all relevant international regulations for chemical transport. Specific packaging details can be provided upon request.
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