3-Iodo-2-methoxypyridine
3-Iodo-2-methoxypyridine (CAS: 112197-15-6), with the molecular formula C6H6INO and a molar mass of 235.02 g/mol, is a halogenated pyridine derivative. It serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceutical intermediates and complex heterocyclic compounds. Its reactive iodine atom allows for diverse coupling reactions, making it a useful reagent for creating advanced molecular structures in research and development.

Organic Synthesis Intermediate
Utilised as a key intermediate in multi-step organic synthesis, enabling the introduction of the 2-methoxypyridine moiety into target molecules. It is particularly effective in cross-coupling reactions like Suzuki, Stille, or Sonogashira couplings.
Pharmaceutical Research
Serves as a critical component in the synthesis of potential drug candidates and pharmaceutical intermediates. Its structure is relevant for developing compounds targeting various biological pathways.
Heterocyclic Chemistry
Acts as a versatile building block for constructing complex heterocyclic systems. The presence of both a pyridine ring and an iodine substituent offers unique reactivity for medicinal chemistry and materials science.
| Molecular weight | 235.02 |
|---|---|
| Empirical formula | C6H6INO |
| Assay | 97% |
| Density | 1.831 g/mL at 25 °C |
| Refractive index | n20/D 1.618 |
| Storage temperature | 2-8°C |


Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H318Causes serious eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3334 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-37/38-41 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Iodo-2-methoxypyridine used for?
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3-Iodo-2-methoxypyridine (CAS: 112197-15-6) is primarily used as a building block and intermediate in organic synthesis, particularly in pharmaceutical research and the development of complex heterocyclic compounds.
What are the CAS number and formula for 3-Iodo-2-methoxypyridine?
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The CAS number for 3-Iodo-2-methoxypyridine is 112197-15-6, and its molecular formula is C6H6INO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Iodo-2-methoxypyridine with a minimum assay of 97%. TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.
How should 3-Iodo-2-methoxypyridine be handled safely?
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3-Iodo-2-methoxypyridine is classified as dangerous (Danger) with hazards including H302 (Harmful if swallowed), H315 (Causes skin irritation), H318 (Causes serious eye damage), and H335 (May cause respiratory irritation). Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, in a well-ventilated area.
How is 3-Iodo-2-methoxypyridine shipped and exported?
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3-Iodo-2-methoxypyridine is shipped according to international regulations, including UN 3334 for air transport. TSS is experienced in global export of chemicals.
How can I request a sample or quote?
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To request a sample or a quote for 3-Iodo-2-methoxypyridine, please contact the Tech Serve Solutions sales team via the website or direct enquiry.
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