3-Indoleglyoxylic acid
3-Indoleglyoxylic acid (CAS: 1477-49-2) is a heterocyclic organic compound with the molecular formula C10H7NO3. As a key building block in chemical synthesis, it serves as a valuable reactant in the preparation of various complex molecules. Its applications span the development of pharmaceutical intermediates, including derivatives of fenbufen and ethacrynic acid, as well as potential anticancer agents and inhibitors of α-Fucosidases.
- IUPAC
- NSC 71954
Synthesis of Pharmaceuticals
This compound is utilised as a reactant in the synthesis of fenbufen and ethacrynic acid derivatives. It is also employed in preparing glyoxyl analogs of indole phytoalexins with potential anticancer properties.
Preparation of Enzyme Inhibitors
3-Indoleglyoxylic acid is a key reactant in the preparation of fuconojirimycin derivatives. These derivatives act as effective inhibitors of α-Fucosidases.
Organic Synthesis Intermediate
It serves as a reactant for the synthesis of tertiary amides. Furthermore, it can be used in the total synthesis of oxazinin-3 via intramolecular addition/cyclization reactions.
| Molecular weight | 189.17 |
|---|---|
| Empirical formula | C10H7NO3 |
| Assay | 98% |
| Storage temperature | 2-8°C |
| Application | • Reactant for synthesis of fenbufen and ethacrynic acid derivatives• Reactant for preparation of glyoxyl analogs of indole phytoalexins as anticancer agents• Reactant for synthesis of tertiary amides• Reactant for preparation of fuconojirimycin derivatives as inhibitors of α-Fucosidases• Reactant for total synthesis of oxazinin-3 from 3-indoleglyoxylic acid via an intramolecular addition/cyclization reactions |
| Melting point | 217 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Indoleglyoxylic acid used for?
+
3-Indoleglyoxylic acid is used as a reactant in the synthesis of fenbufen and ethacrynic acid derivatives, the preparation of glyoxyl analogs of indole phytoalexins with anticancer potential, the synthesis of tertiary amides, and the preparation of fuconojirimycin derivatives as α-Fucosidase inhibitors.
What are the CAS number and chemical formula for 3-Indoleglyoxylic acid?
+
The CAS number for 3-Indoleglyoxylic acid is 1477-49-2, and its chemical formula is C10H7NO3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Indoleglyoxylic acid with an assay of 98%. This product is not supplied as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Indoleglyoxylic acid be handled?
+
3-Indoleglyoxylic acid is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment in a well-ventilated area. Avoid breathing dust and rinse eyes thoroughly if contact occurs (P261, P305 + P351 + P338).
How is 3-Indoleglyoxylic acid packaged and shipped?
+
3-Indoleglyoxylic acid is carefully packaged to maintain its integrity during transit and is available for global export by Tech Serve Solutions.
How can I request a sample or quote for 3-Indoleglyoxylic acid?
+
To request a sample or quote for 3-Indoleglyoxylic acid, please contact the Tech Serve Solutions sales team through our website or by phone.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis