3-Hydroxyphenylboronic acid pinacol ester
3-Hydroxyphenylboronic acid pinacol ester (CAS: 214360-76-6) is an organoboron compound with the molecular formula C12H17BO3 and a molecular weight of 220.07 g/mol. This aryl boronate ester is a valuable building block in organic synthesis, particularly in cross-coupling reactions. It serves as a key intermediate in the preparation of complex organic molecules for pharmaceutical and materials science applications. TSS supplies this compound with a typical assay of 97%.
- IUPAC
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol,3-Hydroxyphenylboronic acid,Pinacol cyclic ester
- Synonyms
- 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenol3-Hydroxyphenylboronic acid, pinacol cyclic ester
Suzuki-Miyaura Cross-Coupling Reactions
3-Hydroxyphenylboronic acid pinacol ester is widely employed as a coupling partner in Suzuki-Miyaura reactions. It facilitates the formation of carbon-carbon bonds with aryl or vinyl halides, enabling the synthesis of biaryl compounds.
Pharmaceutical Intermediate Synthesis
This boronate ester is utilised in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its functional groups allow for versatile derivatization in the construction of complex molecular architectures relevant to drug discovery.
Materials Science Research
The compound finds application in the development of novel organic materials, such as conjugated polymers and organic light-emitting diodes (OLEDs). Its structure can be incorporated into materials to tune electronic and optical properties.
Organic Synthesis Building Block
As a versatile organometallic reagent, it serves as a useful synthon for introducing the 3-hydroxyphenyl moiety into various organic structures. It is a reliable reagent for researchers in academic and industrial settings.
| Molecular weight | 220.07 |
|---|---|
| Empirical formula | C12H17BO3 |
| Assay | 97% |
| Melting point | 94-98 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxyphenylboronic acid pinacol ester used for?
+
3-Hydroxyphenylboronic acid pinacol ester is primarily used as a building block in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions, for the preparation of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and molecular formula for 3-Hydroxyphenylboronic acid pinacol ester?
+
The CAS number is 214360-76-6 and the molecular formula is C12H17BO3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3-Hydroxyphenylboronic acid pinacol ester with a typical assay of 97%. We do not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should 3-Hydroxyphenylboronic acid pinacol ester be handled?
+
Warning: This compound causes skin irritation, serious eye irritation, and may cause respiratory irritation (H315-H319-H335). Always wear appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust. Ensure good ventilation. Store in a well-ventilated place.
Is 3-Hydroxyphenylboronic acid pinacol ester a controlled substance?
+
Based on the provided data, 3-Hydroxyphenylboronic acid pinacol ester is not listed as a controlled substance.
How is 3-Hydroxyphenylboronic acid pinacol ester packed and shipped?
+
3-Hydroxyphenylboronic acid pinacol ester is carefully packed to ensure safe transit and is exported globally by TSS. Specific packaging details are available upon request.
How can I request a quote or sample for 3-Hydroxyphenylboronic acid pinacol ester?
+
To request a quote or sample of 3-Hydroxyphenylboronic acid pinacol ester, please contact our sales team through the website or provide your details via the enquiry form.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis