3-Hydroxyphenylboronic acid
3-Hydroxyphenylboronic acid (CAS: 87199-18-6, Formula: HOC6H4B(OH)2, MW: 137.93) is an organoboron compound with a hydroxyl substituent on the phenyl ring. This versatile building block is primarily employed in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. It serves as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials, enabling the construction of complex molecular architectures.
- IUPAC
- 3-Hydroxybenzeneboronic acid,m-Hydroxybenzeneboronic acid
- Synonyms
- 3-Hydroxybenzeneboronic acidm-Hydroxybenzeneboronic acid
Suzuki-Miyaura Cross-Coupling
3-Hydroxyphenylboronic acid is extensively used as a coupling partner in palladium-catalysed Suzuki-Miyaura reactions. This enables the synthesis of biaryl compounds and other complex organic molecules.
Pharmaceutical Intermediate
It serves as a crucial building block in the multi-step synthesis of various active pharmaceutical ingredients (APIs). Its structure allows for targeted functionalisation in drug discovery programmes.
Materials Science
This boronic acid derivative can be incorporated into the synthesis of functional materials, such as organic light-emitting diodes (OLEDs) or polymers, due to its unique electronic and structural properties.
Agrochemical Synthesis
Used in the development of novel pesticides and herbicides, 3-Hydroxyphenylboronic acid contributes to the creation of molecules with specific biological activities.
| Molecular weight | 137.93 |
|---|---|
| Linear formula | HOC6H4B(OH)2 |
| Assay | ≥95.0% |
| Melting point | 210-213 °C (dec.)(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxyphenylboronic acid used for?
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3-Hydroxyphenylboronic acid is primarily used in organic synthesis, particularly in Suzuki-Miyaura cross-coupling reactions for the formation of carbon-carbon bonds. It acts as a key intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and chemical formula for 3-Hydroxyphenylboronic acid?
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The CAS number for 3-Hydroxyphenylboronic acid is 87199-18-6 and its chemical formula is HOC6H4B(OH)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxyphenylboronic acid with an assay of ≥95.0%. This product is typically supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or any pharmacopoeia grade.
How should 3-Hydroxyphenylboronic acid be handled?
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Handling 3-Hydroxyphenylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with a WGK of 3 in Germany.
Is 3-Hydroxyphenylboronic acid a controlled substance?
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Based on the provided data, 3-Hydroxyphenylboronic acid is not indicated as a controlled substance.
How is 3-Hydroxyphenylboronic acid packed and shipped?
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3-Hydroxyphenylboronic acid is carefully packed to ensure stability during transit and is exported globally by Tech Serve Solutions.
How can I request a quote or sample for 3-Hydroxyphenylboronic acid?
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To request a quote or a sample of 3-Hydroxyphenylboronic acid, please contact our sales team through the TSS website or by phone.
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