3-Hydroxyphenylacetylene
3-Hydroxyphenylacetylene (CAS: 10401-11-3, C8H6O) is a valuable organic building block with a molecular weight of 118.13 g/mol. This terminal alkyne offers a reactive functional group suitable for diverse chemical syntheses. It serves as a key intermediate in the development of complex organic molecules, finding utility in research and industrial applications where precise chemical structure modification is paramount. Its properties make it a versatile component in synthetic organic chemistry.
- IUPAC
- 3-Ethynylphenol
- Synonyms
- 3-Ethynylphenol

Organic Synthesis Intermediate
Utilised as a building block in the synthesis of complex organic molecules and novel compounds. Its terminal alkyne functionality allows for various coupling and addition reactions.
Pharmaceutical Research
Serves as a precursor or intermediate in the research and development of pharmaceutical agents. The hydroxyphenylacetylene moiety can be incorporated into potential drug candidates.
Material Science
Can be employed in the synthesis of specialised polymers or functional materials where its unique structural features are advantageous.
| Molecular weight | 118.13 |
|---|---|
| Empirical formula | C8H6O |
| Assay | ≥95.0% |
| Density | 1.083 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5840(lit.) |


Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 103 °C / 217.4 °F |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41-52/53 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxyphenylacetylene used for?
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3-Hydroxyphenylacetylene (CAS: 10401-11-3, C8H6O) is primarily used as an organic building block and intermediate in chemical synthesis, particularly in pharmaceutical research and material science.
What is the CAS number and formula for 3-Hydroxyphenylacetylene?
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The CAS number for 3-Hydroxyphenylacetylene is 10401-11-3, and its empirical formula is C8H6O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxyphenylacetylene with an assay of ≥95.0%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Hydroxyphenylacetylene be handled safely?
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3-Hydroxyphenylacetylene is classified as dangerous. It is harmful if swallowed and causes serious eye damage (H302-H318). Handling requires appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection. Consult the Safety Data Sheet for full details.
Is 3-Hydroxyphenylacetylene a controlled substance?
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The provided data does not indicate that 3-Hydroxyphenylacetylene is a controlled substance.
How is 3-Hydroxyphenylacetylene packed and exported?
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Tech Serve Solutions, as a specialist global supplier, packs and exports chemicals according to international shipping regulations to ensure safe and compliant delivery worldwide.
How can I request a quote or sample for 3-Hydroxyphenylacetylene?
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To request a quote or sample of 3-Hydroxyphenylacetylene, please contact our sales team through the website or via direct inquiry, providing your specific requirements.
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