3-Hydroxypiperidine
3-Hydroxypiperidine (CAS: 6859-99-0, C5H11NO) is a heterocyclic organic compound with a molecular weight of 101.15 g/mol. Available at ≥98.0% purity, this piperidine derivative serves as a key reactant in various chemical syntheses. Its applications include the preparation of unsymmetrical ureas, piperidine nucleoside analogues, and substituted pyridines, as well as its use in fluorination reactions.
- IUPAC
- 3-Piperidinol
- Synonyms
- 3-Piperidinol

Synthesis of Unsymmetrical Ureas
3-Hydroxypiperidine acts as a reactant in the synthesis of unsymmetrical ureas, contributing to the development of novel organic compounds.
Piperidine Nucleoside Analogue Synthesis
It is employed in the creation of piperidine nucleoside analogues, which are of interest in medicinal chemistry research.
Fluorination Reactions
This compound finds utility as a reactant in various fluorination reactions, enabling the introduction of fluorine atoms into organic molecules.
Substituted Pyridine Synthesis
3-Hydroxypiperidine is a valuable building block for synthesising a range of substituted pyridine derivatives.
| Molecular weight | 101.15 |
|---|---|
| Empirical formula | C5H11NO |
| Assay | ≥98.0% (NT) |
| Solubility | H2O: soluble1 g/mL, clear |
| Storage temperature | 2-8°C |
| Application | Reactant for: Synthesis of unsymmetrical ureas1 Synthesis of piperidine nucleoside analogs2 Fluorination reactions3 Synthesis of substituted pyridines4 |
| Melting point | 57-61 °C |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >100 °C / >212 °F |
| Transport (UN / ADR) | UN 3263 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxypiperidine used for?
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3-Hydroxypiperidine is used as a reactant in the synthesis of unsymmetrical ureas, piperidine nucleoside analogues, and substituted pyridines, and in fluorination reactions.
What is the CAS number and formula for 3-Hydroxypiperidine?
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The CAS number is 6859-99-0 and the empirical formula is C5H11NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxypiperidine with an assay of ≥98.0% (NT). We do not represent this product as USP, BP, or EP grade.
How should 3-Hydroxypiperidine be handled safely?
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3-Hydroxypiperidine is classified as Danger with hazard statement H314 (Causes severe skin burns and eye damage). Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection, is essential. Handle in accordance with safety data sheet instructions.
Is 3-Hydroxypiperidine suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Hydroxypiperidine.
How can I request a sample or quote for 3-Hydroxypiperidine?
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Please contact our sales team to request a sample or a quotation for 3-Hydroxypiperidine.
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