3-Hydroxy-4-methyl-2(3H)-thiazolethione
3-Hydroxy-4-methyl-2(3H)-thiazolethione (CAS 49762-08-5) is a heterocyclic organic compound with the molecular formula C4H5NOS2 and a molecular weight of 147.22 g/mol. It is recognised for its utility as a building block in chemical synthesis. Notably, this compound is employed in the Barton reaction, facilitating the generation of carbon radicals through the decarboxylative rearrangement of associated esters.
- IUPAC
- 2-Mercapto-4-methylthiazole 3-oxide
Barton Reaction Reagent
This compound serves as a key reagent in the Barton reaction. It enables the formation of carbon radicals via a decarboxylative rearrangement mechanism when used with appropriate ester substrates.
Heterocyclic Building Block
As a thiazole derivative, it functions as a versatile building block in organic synthesis. Its structure allows for further functionalization and incorporation into more complex molecular architectures.
Radical Chemistry Intermediate
It is specifically useful for generating carbon radicals, which are reactive intermediates employed in various synthetic transformations and mechanistic studies.
| Molecular weight | 147.22 |
|---|---|
| Empirical formula | C4H5NOS2 |
| Assay | 97% |
| Application | Useful in the Barton reaction for the generation of carbon radicals through decarboxylative rearrangement of the corresponding esters.1 |
| Melting point | 92-94 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxy-4-methyl-2(3H)-thiazolethione used for?
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3-Hydroxy-4-methyl-2(3H)-thiazolethione is primarily used in the Barton reaction for the generation of carbon radicals through decarboxylative rearrangement of corresponding esters. It also serves as a heterocyclic building block in chemical synthesis.
What is the CAS number and formula for 3-Hydroxy-4-methyl-2(3H)-thiazolethione?
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The CAS number for 3-Hydroxy-4-methyl-2(3H)-thiazolethione is 49762-08-5, and its empirical formula is C4H5NOS2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxy-4-methyl-2(3H)-thiazolethione with a minimum purity of 97%. TSS does not represent this product as USP, BP, or EP grade.
How should 3-Hydroxy-4-methyl-2(3H)-thiazolethione be handled safely?
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Handling requires appropriate personal protective equipment, including a dust mask (N95 type US), eyeshields, and gloves. Avoid inhalation of dust, ensure adequate ventilation, and prevent contact with eyes and skin. Refer to the Safety Data Sheet for comprehensive safety information.
Is 3-Hydroxy-4-methyl-2(3H)-thiazolethione a controlled substance?
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The provided data does not indicate that 3-Hydroxy-4-methyl-2(3H)-thiazolethione is a controlled substance.
How is this chemical shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter, can arrange for the shipment and export of 3-Hydroxy-4-methyl-2(3H)-thiazolethione. Specific packaging and shipping details will be confirmed upon order.
How can I request a quote or sample?
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To request a quote or a sample of 3-Hydroxy-4-methyl-2(3H)-thiazolethione, please contact the Tech Serve Solutions sales department through the website or by phone.
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