3-Hydroxy-4-methoxycinnamic acid, predominantly trans
3-Hydroxy-4-methoxycinnamic acid (CAS: 537-73-5) is a cinnamic acid derivative with the molecular formula C10H10O4 and a molecular weight of 194.18 g/mol. This compound is primarily utilised as a chemical building block in organic synthesis. It has found application in the development of pharmaceutical compounds, notably in the synthesis of tranilast and its analogues. Available from Tech Serve Solutions with an assay of 97%.
- Synonyms
- 3-Hydroxy-4-methoxycinnamic acidIsoferulic acid
Synthesis of Tranilast Analogues
3-Hydroxy-4-methoxycinnamic acid served as a precursor in the microbial synthesis of tranilast and related cinnamoyl anthranilates. This process was achieved using genetically engineered Saccharomyces cerevisiae yeast strains.
Organic Building Block
As a carboxylic acid and a derivative of cinnamic acid, this compound functions as a versatile building block in complex organic synthesis pathways. Its structure lends itself to further chemical modifications and incorporation into larger molecules.
Chemical Synthesis Intermediate
The compound is employed as an intermediate in various chemical synthesis routes. Its utility spans the creation of diverse organic compounds and functionalised molecules relevant to research and development.
| Molecular weight | 194.18 |
|---|---|
| Linear formula | HOC6H3(OCH3)CH=CHCO2H |
| Assay | 97% |
| Application | 3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain1. |
| Melting point | 230 °C (dec.)(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Hydroxy-4-methoxycinnamic acid primarily used for?
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3-Hydroxy-4-methoxycinnamic acid is principally used as a building block in organic synthesis, including the synthesis of tranilast and its analogues.
What are the CAS number and molecular formula for 3-Hydroxy-4-methoxycinnamic acid?
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The CAS number for 3-Hydroxy-4-methoxycinnamic acid is 537-73-5. Its linear formula is HOC6H3(OCH3)CH=CHCO2H, and its molecular weight is 194.18 g/mol.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Hydroxy-4-methoxycinnamic acid with an assay of 97%. This is a technical/research grade material; TSS does not represent it as USP, BP, EP, or any other pharmacopoeia grade.
How should 3-Hydroxy-4-methoxycinnamic acid be handled safely?
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This compound is classified as an irritant. Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Ensure adequate ventilation and avoid inhalation of dust and contact with skin and eyes.
Is 3-Hydroxy-4-methoxycinnamic acid available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Hydroxy-4-methoxycinnamic acid, complying with international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quote for 3-Hydroxy-4-methoxycinnamic acid, please contact our sales team through the website or by calling our customer service number.
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