3-Hydroxy-4-nitrobenzaldehyde

CAS 704-13-2HOC6H3(NO2)CHOChemical Synthesis

3-Hydroxy-4-nitrobenzaldehyde (CAS 704-13-2) is an organic compound with the formula HOC6H3(NO2)CHO and a molecular weight of 167.12 g/mol. This nitro-substituted aromatic aldehyde serves as a valuable building block in chemical synthesis. It has been utilized in studies involving enantioselective reactions and as a substrate for investigating enzyme mechanisms, particularly in biochemical research.

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3-Hydroxy-4-nitrobenzaldehyde (HOC6H3(NO2)CHO) — chemical structure, CAS 704-13-2; Chemistry, fine chemical supplied by Tech Serve Solutions

AldehydesBuilding BlocksCarbonyl CompoundsChemical Synthesis

01 /Applications

Enantioselective Aldol Reactions

This compound functions as an aldehyde component in the study of enantioselective thioester aldol reactions, often catalysed by metal complexes.

Enzyme Mechanism Probing

It has been employed as a chromophoric substrate to investigate the catalytic mechanisms of enzymes such as horse liver alcohol dehydrogenase.

Organic Synthesis Intermediate

As a functionalized benzaldehyde derivative, it is a useful intermediate in the synthesis of more complex organic molecules.

02 /Properties

Molecular weight	167.12
Linear formula	HOC6H3(NO2)CHO
Assay	97%
Application	3-Hydroxy-4-nitrobenzaldehyde is the aldehyde component in a study of an enantioselective thioester aldol reaction. This reaction has been catalyzed by copper(II) triflate in the presence of a chiral bisoxazoline ligand.1 The product has been used as a chromophoric substrate for probing the catalytic mechanism of horse liver alcohol dehydrogenase.2
Melting point	127-131 °C(lit.)

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

704-13-2

MDL number

MFCD00007109

PubChem substance

24849596

Beilstein registry

2556882

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Hydroxy-4-nitrobenzaldehyde used for?

3-Hydroxy-4-nitrobenzaldehyde is used as a building block in organic synthesis, particularly in studies of enantioselective reactions and enzyme mechanisms.

What are the CAS number and formula for 3-Hydroxy-4-nitrobenzaldehyde?

The CAS number is 704-13-2 and the chemical formula is HOC6H3(NO2)CHO.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies 3-Hydroxy-4-nitrobenzaldehyde with an assay of 97%. This product is not supplied as USP, BP, EP, or other pharmacopoeia grades.

How should 3-Hydroxy-4-nitrobenzaldehyde be handled safely?

Handle with appropriate personal protective equipment, including a dust mask (N95 US type), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as an irritant to skin, eyes, and the respiratory tract (H315-H319-H335).

How is 3-Hydroxy-4-nitrobenzaldehyde packed, shipped, and exported?

Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping and customs regulations. Packing is designed to ensure product integrity during transit.