3-Fluoro-5-(trifluoromethyl)phenyl isocyanate
3-Fluoro-5-(trifluoromethyl)phenyl isocyanate (CAS: 302912-19-2; Formula: FC6H3(CF3)NCO; MW: 205.11) is a fluorinated aromatic building block. This compound serves as a valuable intermediate in organic synthesis, particularly for introducing the 3-fluoro-5-(trifluoromethyl)phenyl moiety into more complex molecules. Its reactivity as an isocyanate makes it suitable for reactions with nucleophiles like amines and alcohols, forming carbamates and ureas. It is supplied by TSS for research and development purposes.
Organic Synthesis Intermediate
Utilised in the synthesis of novel organic compounds, pharmaceutical intermediates, and agrochemicals. The trifluoromethyl and fluorine substituents can impart unique electronic and lipophilic properties to target molecules.
Building Block for Fluorinated Materials
Serves as a key building block for creating advanced materials with specific thermal and chemical resistance properties, leveraging the stability of fluorinated aromatic systems.
Research and Development
Employed in academic and industrial laboratories for exploring new reaction pathways and developing new chemical entities. Its specific structure allows for targeted modifications in drug discovery programmes.
| Molecular weight | 205.11 |
|---|---|
| Linear formula | FC6H3(CF3)NCO |
| Assay | 97% |
| Boiling point | 164 °C(lit.) |
| Density | 1.423 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.446(lit.) |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38-42 |
| Safety statements (S) | 23-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-5-(trifluoromethyl)phenyl isocyanate used for?
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3-Fluoro-5-(trifluoromethyl)phenyl isocyanate is primarily used as a building block and intermediate in organic synthesis, including the development of pharmaceuticals and advanced materials.
What is the CAS number and chemical formula for this product?
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The CAS number is 302912-19-2, and the chemical formula is FC6H3(CF3)NCO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-5-(trifluoromethyl)phenyl isocyanate with a minimum purity of 97%. This product is intended for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Fluoro-5-(trifluoromethyl)phenyl isocyanate be handled safely?
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This compound is dangerous and requires careful handling. It is harmful if swallowed, inhaled, or in contact with skin, causes skin and serious eye irritation, and may cause respiratory irritation. It can also cause allergy or asthma symptoms or breathing difficulties if inhaled. Always use appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, and handle in a well-ventilated area or fume hood.
Is this product controlled or scheduled?
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The provided data does not indicate that this compound is a controlled or scheduled substance.
How is this chemical exported and shipped?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Specific shipping and export details will be provided upon inquiry, adhering to all relevant regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or obtain a quote for 3-Fluoro-5-(trifluoromethyl)phenyl isocyanate, please contact our sales team via the website or listed contact information.
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