3-Fluoro-p-anisidine
3-Fluoro-p-anisidine (CAS: 366-99-4), with the chemical formula FC6H3(OCH3)NH2 and a molecular weight of 141.14 g/mol, is a fluorinated aromatic amine. This compound serves as a valuable building block in organic synthesis. It is primarily utilised in the development of pharmaceuticals, agrochemicals, and other specialised organic compounds where precise functionalisation is required. Tech Serve Solutions offers this chemical with a purity of 98%.
- IUPAC
- 3-Fluoro-4-methoxyaniline
- Synonyms
- 3-Fluoro-4-methoxyaniline

Pharmaceutical Intermediate
3-Fluoro-p-anisidine is employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its unique structural features can be incorporated to modulate drug properties such as efficacy and metabolism.
Agrochemical Synthesis
This compound acts as a precursor for the creation of novel pesticides and herbicides. The introduction of fluorine can enhance the biological activity and stability of agrochemical agents.
Organic Building Block
As a versatile fluorinated building block, it is used in research and development for the synthesis of complex organic molecules and functional materials. Its reactivity allows for various coupling and derivatisation reactions.
| Molecular weight | 141.14 |
|---|---|
| Linear formula | FC6H3(OCH3)NH2 |
| Assay | 98% |
| Boiling point | 135 °C/18 mmHg(lit.) |
| Melting point | 81-83 °C(lit.) |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-p-anisidine used for?
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3-Fluoro-p-anisidine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What are the CAS number and chemical formula for 3-Fluoro-p-anisidine?
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The CAS number is 366-99-4, and the chemical formula is FC6H3(OCH3)NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-p-anisidine with an assay of 98%. TSS does not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with 3-Fluoro-p-anisidine?
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3-Fluoro-p-anisidine is classified as harmful if swallowed, in contact with skin, or if inhaled. It also causes skin irritation, serious eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including a dust mask (N95), eye shields, and gloves, should be used.
How is 3-Fluoro-p-anisidine typically packed and exported?
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Tech Serve Solutions packs and exports chemicals according to international shipping regulations to ensure safe transit. Specific packaging details are available upon request.
How can I request a sample or quote for 3-Fluoro-p-anisidine?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number (366-99-4).
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