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3-Fluoroaniline

CAS 372-19-0FC6H4NH2Chemical Synthesis

3-Fluoroaniline (CAS: 372-19-0; Formula: FC6H4NH2; Molar Mass: 111.12 g/mol) is a key fluorinated aromatic amine. This versatile building block is extensively used in organic synthesis for the creation of complex molecules, particularly within the pharmaceutical and agrochemical industries. Its unique structure, featuring a fluorine atom on the phenyl ring adjacent to the amine group, allows for specific chemical reactivity essential for drug discovery and material science.

IUPAC
1-Amino-3-fluorobenzene
Synonyms
1-Amino-3-fluorobenzene
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3-Fluoroaniline (FC6H4NH2) — chemical structure, CAS 372-19-0; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisFluorinated Building Blocks
01 /Applications

Pharmaceutical Intermediates

3-Fluoroaniline serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs). Its fluorinated nature can enhance metabolic stability, lipophilicity, and binding affinity of drug candidates.

Agrochemical Synthesis

This compound is employed in the development of novel pesticides, herbicides, and fungicides. The incorporation of fluorine can improve the efficacy and environmental profile of agrochemical products.

Material Science

Used in the synthesis of specialized polymers and advanced materials where the unique electronic properties conferred by the fluorine atom are beneficial.

Research and Development

A valuable reagent for academic and industrial research laboratories engaged in exploring new synthetic routes and chemical entities.

02 /Properties
Molecular weight111.12
Linear formulaFC6H4NH2
Assay99%
Gradetechnical
Boiling point186 °C/756 mmHg(lit.)
Density1.156 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.542(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Danger

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H318Causes serious eye damage
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
Protective equipmentEyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point77 °C / 170.6 °F
Transport (UN / ADR)UN 2941 6.1 / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)Xn
Risk statements (R)22-37/38-41
Safety statements (S)26-36/39

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
372-19-0
MDL number
MFCD00007758
PubChem substance
24870221
Beilstein registry
1305471
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 3-Fluoroaniline used for?

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3-Fluoroaniline is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and advanced materials.

What are the CAS number and formula for 3-Fluoroaniline?

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The CAS number for 3-Fluoroaniline is 372-19-0, and its chemical formula is FC6H4NH2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 3-Fluoroaniline with a minimum assay of 99% and a technical grade. We do not represent this product as USP, BP, or EP grade.

How should 3-Fluoroaniline be handled safely?

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3-Fluoroaniline is classified as dangerous. It is harmful if swallowed, causes skin irritation, causes serious eye damage, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, face shields, and suitable gloves and respirators, must be used. Handle in a well-ventilated area and avoid breathing vapours.

Does Tech Serve Solutions export 3-Fluoroaniline?

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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3-Fluoroaniline, serving customers worldwide.

How can I request a quote or sample for 3-Fluoroaniline?

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To request a quote or sample, please contact our sales team through the website or by phone, providing your specific requirements.

Need 3-Fluoroaniline in a specific grade or volume?