3-Fluorobenzamide
3-Fluorobenzamide (CAS 455-37-8), with the linear formula FC₆H₄CONH₂, is a key organic building block and fluorinated intermediate. Possessing a molecular weight of 139.13 g/mol, this compound serves as a versatile reagent in chemical synthesis. Its primary application involves its use in the creation of more complex molecules, particularly in the field of pharmaceutical research and development, contributing to the exploration of novel chemical entities.
Synthesis of Phosphoric Triamides
3-Fluorobenzamide is utilised as a precursor in the synthesis of specific phosphoric triamide derivatives. For instance, it has been employed in the preparation of <i>N</i>-(3-fluorobenzoyl)-<i>N′,N′′</i>-<i>bis</i>(4-methylphenyl)phosphoric triamide, demonstrating its utility in constructing complex organophosphorus compounds.
Fluorinated Organic Building Block
As a fluorinated aryl building block, 3-Fluorobenzamide is instrumental in introducing the 3-fluorobenzoyl moiety into various organic molecules. This functionality is valuable in medicinal chemistry and materials science for modulating physicochemical and biological properties.
Chemical Synthesis Intermediate
The compound acts as a crucial intermediate in multi-step organic syntheses. Its reactive amide group and the presence of a fluorine atom on the aromatic ring make it a useful starting material for a range of chemical transformations.
| Molecular weight | 139.13 |
|---|---|
| Linear formula | FC6H4CONH2 |
| Assay | 99% |
| Application | 3-Fluorobenzamide has been used in the synthesis of N-(3-fluorobenzoyl)-N′,N′′-bis(4-methylphenyl)phosphoric triamide1. |
| Melting point | 129-132 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluorobenzamide primarily used for?
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3-Fluorobenzamide is primarily used as a building block in organic synthesis, particularly in the preparation of fluorinated compounds and intermediates for research, including the synthesis of phosphoric triamides.
What are the CAS number and formula for 3-Fluorobenzamide?
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The CAS number for 3-Fluorobenzamide is 455-37-8, and its linear formula is FC₆H₄CONH₂.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluorobenzamide with an assay of 99%. This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia applications.
What are the main safety hazards associated with 3-Fluorobenzamide?
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3-Fluorobenzamide is classified as a warning substance, with hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including gloves, eye protection, and respiratory protection, should be used when handling this chemical in a well-ventilated area.
Is 3-Fluorobenzamide available for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Fluorobenzamide, and can fulfil international orders.
How can I request a sample or a quote for 3-Fluorobenzamide?
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To request a sample or a quote for 3-Fluorobenzamide, please contact our sales department through the website or by phone. Our team will be pleased to assist with your inquiry.
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