3-Fluoro-5-(trifluoromethyl)benzoyl chloride
3-Fluoro-5-(trifluoromethyl)benzoyl chloride (CAS: 171243-30-4) is a fluorinated organic building block with the molecular formula FC6H3(CF3)COCl and a molecular weight of 226.56 g/mol. As an acid halide, it is a reactive intermediate primarily utilised in chemical synthesis. It serves as a valuable precursor for introducing the 3-fluoro-5-(trifluoromethyl)benzoyl moiety into more complex molecules, finding applications in the development of pharmaceuticals and agrochemicals.
Pharmaceutical Intermediate
This compound is employed as a key building block in the synthesis of active pharmaceutical ingredients (APIs). Its fluorinated structure can impart desirable pharmacokinetic properties to drug candidates.
Agrochemical Synthesis
It functions as a precursor in the creation of novel agrochemicals, such as herbicides, insecticides, and fungicides, where the trifluoromethyl group often enhances biological activity.
Organic Synthesis Reagent
As a reactive benzoyl chloride derivative, it is used in acylation reactions to introduce the 3-fluoro-5-(trifluoromethyl)benzoyl group into various organic molecules.
Material Science
Fluorinated aromatic compounds can be incorporated into polymers or advanced materials to modify their properties, such as thermal stability and hydrophobicity.
| Molecular weight | 226.56 |
|---|---|
| Linear formula | FC6H3(CF3)COCl |
| Assay | 95% |
| Boiling point | 119 °C(lit.) |
| Density | 1.482 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.462(lit.) |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 74 °C / 165.2 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-Fluoro-5-(trifluoromethyl)benzoyl chloride used for?
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3-Fluoro-5-(trifluoromethyl)benzoyl chloride is primarily used as a building block in organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It acts as a reagent for introducing the 3-fluoro-5-(trifluoromethyl)benzoyl group into target molecules.
What is the CAS number and chemical formula?
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The CAS number for 3-Fluoro-5-(trifluoromethyl)benzoyl chloride is 171243-30-4. The linear formula is FC6H3(CF3)COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3-Fluoro-5-(trifluoromethyl)benzoyl chloride with a minimum assay of 95%. We do not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should 3-Fluoro-5-(trifluoromethyl)benzoyl chloride be handled safely?
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Due to its corrosive nature (H314), handle this compound with extreme care. Use appropriate personal protective equipment, including chemical-resistant gloves, eye protection (goggles and a face shield), and respiratory protection (type ABEK respirator filter). Ensure adequate ventilation and avoid contact with skin, eyes, and clothing. Refer to the Safety Data Sheet for comprehensive handling instructions.
Is 3-Fluoro-5-(trifluoromethyl)benzoyl chloride shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 3-Fluoro-5-(trifluoromethyl)benzoyl chloride, and can arrange for international shipment.
How can I request a quote or sample?
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To request a quote or a sample of 3-Fluoro-5-(trifluoromethyl)benzoyl chloride, please contact our sales team through the provided channels on our website, specifying your requirements.
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