Ala-Gln
Ala-Gln (CAS: 39537-23-0), with the chemical formula C8H15N3O4 and a molecular weight of 217.22 g/mol, is a dipeptide. It serves as a stabilized and more efficient source of L-glutamine for cell culture applications. By utilizing Ala-Gln, researchers can effectively supplement cell media while mitigating the ammonia build-up often associated with free L-glutamine. This compound is crucial for maintaining optimal conditions in various bioprocessing and research environments.
- IUPAC
- Alanyl-glutamine,Glutamine-S
- Synonyms
- Alanyl-glutamineGlutamine-S

Stabilized L-Glutamine Source
Ala-Gln is employed in cell culture media as a superior alternative to free L-glutamine. It provides a stable delivery form of glutamine, essential for cellular metabolism and growth.
Reduced Ammonia Generation
A primary benefit of using Alanyl-L-glutamine is its ability to significantly decrease the production of ammonia during cell culture. This reduction is critical for maintaining cell viability and consistent experimental results.
Cell Culture Media Supplementation
This dipeptide is incorporated into various mammalian and microbial cell culture formulations to support robust cell proliferation and productivity in biopharmaceutical research and manufacturing.
| Molecular weight | 217.22 |
|---|---|
| Empirical formula | C8H15N3O4 |
| Assay | ≥98% (TLC) |
| Application | L-Glutamine is an essential supplement for cell culture. The free amino acid L-glutamine is unstable and degrades to pyroglutamate. Alanyl-L-glutamine (Ala-Gln) and Gylcyl-L-glutamine (Gly-Gln) are used in cell culture as alternative delivery forms of stabilized L-glutamine. The primary advantage of using L-alanylglutamine in place of L-glutamine is that it reduces the level of ammonia generated during cell culture.1,2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 1 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ala-Gln used for?
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Ala-Gln is primarily used as a stable source of L-glutamine in cell culture media, offering a reduced ammonia generation compared to free L-glutamine.
What is the CAS number and chemical formula for Ala-Gln?
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The CAS number for Ala-Gln is 39537-23-0, and its empirical formula is C8H15N3O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ala-Gln with a purity of ≥98% (TLC). We do not represent this product as USP, BP, or EP grade.
How should Ala-Gln be handled?
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When handling Ala-Gln, it is recommended to wear eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible.
Is Ala-Gln a controlled substance?
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The provided data does not indicate that Ala-Gln (CAS: 39537-23-0) is a controlled substance.
How is Ala-Gln packed and shipped?
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Ala-Gln is packed and exported by Tech Serve Solutions adhering to industry standards for chemical handling and transport.
How can I request a quote or sample for Ala-Gln?
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To request a quote or sample for Ala-Gln, please contact the Tech Serve Solutions sales team through our website or by phone.
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