(3-Benzyloxypropyl)triphenylphosphonium bromide
(3-Benzyloxypropyl)triphenylphosphonium bromide (CAS: 54314-85-1) is a quaternary phosphonium salt with the molecular formula C 6 H 5 CH 2 O(CH 2 ) 3 P(C 6 H 5 ) 3 Br and a molecular weight of 491.40 g/mol. This compound serves as a valuable reactant in organic synthesis, particularly in C-C bond formation and olefination reactions. It is a key reagent for preparing complex molecules, including spirocyclohexadienones and potential antitumor agents.
Preparation of Spirocyclohexadienones
Utilised as a reactant for the synthesis of spirocyclohexadienones through Palladium-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation reactions.
Synthesis of Hsp90 Inhibitors
Employed in the preparation of inhibitors targeting heat shock protein 90 (Hsp90), which have shown potential as antitumor agents.
Carpanone-like Molecule Synthesis
Serves as a precursor in synthetic routes leading to carpanone-like molecules, often involving an oxidative coupling and Diels-Alder cycloaddition sequence.
| Molecular weight | 491.40 |
|---|---|
| Linear formula | C6H5CH2O(CH2)3P(C6H5)3Br |
| Assay | 98% |
| Application | Reactant for preparation of:• Spirocyclohexadienones via Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation1• Inhibitors of heat shock protein (Hsp90) as antitumor agents2• Carpanone-like molecules via an oxidative coupling/Diels-Alder cycloaddition sequence3 |
| Melting point | 153-154 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3-Benzyloxypropyl)triphenylphosphonium bromide used for?
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It is used as a reactant in organic synthesis, particularly for C-C bond formation, olefination, and the preparation of spirocyclohexadienones, Hsp90 inhibitors, and carpanone-like molecules.
What are the CAS number and formula for (3-Benzyloxypropyl)triphenylphosphonium bromide?
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The CAS number is 54314-85-1 and the linear formula is C 6 H 5 CH 2 O(CH 2 ) 3 P(C 6 H 5 ) 3 Br.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should (3-Benzyloxypropyl)triphenylphosphonium bromide be handled?
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This compound is a Warning: Causes skin irritation, serious eye irritation, and may cause respiratory irritation. Handle with adequate ventilation and wear appropriate personal protective equipment, including a dust mask type N95, eyeshields, and gloves.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled.
How is (3-Benzyloxypropyl)triphenylphosphonium bromide packed, shipped, and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Products are carefully packed according to international shipping regulations for safe transport.
How can I request a quote or sample?
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Please contact our sales team via the website or direct email to request a quotation or a sample for evaluation.
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