(3-Aminopropyl)trimethoxysilane
(3-Aminopropyl)trimethoxysilane (CAS: 13822-56-5; Formula: H2N(CH2)3Si(OCH3)3; MW: 179.29 g/mol) is a versatile organosilicon compound featuring both an amine and a trimethoxysilyl functional group. This dual reactivity makes it valuable in various chemical synthesis applications, particularly as a coupling agent and surface modifier. It is widely utilized to improve adhesion between organic polymers and inorganic substrates, enhancing the performance of composite materials and coatings.
- IUPAC
- 3-(Trimethoxysilyl)propylamine
- Synonyms
- 3-(Trimethoxysilyl)propylamine

Coupling Agent
This silane acts as a crosslinker, forming strong bonds between inorganic fillers (like silica or glass fibers) and organic polymer matrices. This integration significantly enhances mechanical properties, durability, and moisture resistance in composite materials.
Surface Modification
It can be used to modify the surface properties of inorganic materials, rendering them more compatible with organic systems. This application is crucial in areas such as adhesion promotion for coatings, paints, and sealants applied to glass or metal substrates.
Chemical Synthesis Intermediate
The presence of both amine and alkoxysilane groups makes it a useful building block in the synthesis of more complex organosilicon compounds and functionalized polymers.
| Molecular weight | 179.29 |
|---|---|
| Linear formula | H2N(CH2)3Si(OCH3)3 |
| Assay | 97% |
| Grade | purum |
| Form | liquid |
| Boiling point | 91-92 °C/15 mmHg(lit.) |
| Density | 1.027 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.424(lit.) |

Hazard statements
- H315Causes skin irritation
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 90 °C / 194 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 38-41 |
| Safety statements (S) | 26-39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (3-Aminopropyl)trimethoxysilane used for?
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(3-Aminopropyl)trimethoxysilane is primarily used as a coupling agent to improve adhesion between inorganic materials and organic polymers, and for surface modification of inorganic substrates. It also serves as an intermediate in chemical synthesis.
What is the CAS number and formula for (3-Aminopropyl)trimethoxysilane?
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The CAS number is 13822-56-5 and the chemical formula is H2N(CH2)3Si(OCH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (3-Aminopropyl)trimethoxysilane with a purity of 97% (purum grade). TSS does not represent this product as USP, BP, or EP grade.
How should (3-Aminopropyl)trimethoxysilane be handled?
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This compound is classified as corrosive and causes serious eye damage (H318) and skin irritation (H315). Always wear appropriate personal protective equipment, including eyeshields and chemical-resistant gloves. Ensure good ventilation and avoid contact with skin, eyes, and clothing.
How is this chemical packed and shipped?
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Products are carefully packed in compliance with international shipping regulations. TSS exports fine chemicals, pharmaceutical intermediates, and laboratory reagents globally.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quotation or a sample of (3-Aminopropyl)trimethoxysilane.
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