N-tert-Butylhydroxylamine hydrochloride
N-tert-Butylhydroxylamine hydrochloride (CAS: 57497-39-9), with the linear formula (CH₃)₃CNHOH·HCl and a molecular weight of 125.60 g/mol, is a valuable organic compound. It functions as a specialised building block in chemical synthesis. Its primary utility lies in applications such as spin trapping of short-lived radicals and the synthesis of complex organic molecules like α-ketoamides and spirocyclopropanated azetidinones.
Spin Trapping of Radicals
N-tert-Butylhydroxylamine hydrochloride is employed in the spin trapping of transient, short-lived radicals. This technique is crucial for studying radical reaction mechanisms in various chemical and biological systems.
Synthesis of α-Ketoamides
This compound serves as a reagent in the synthetic pathways leading to α-ketoamides. These structures are important intermediates in organic chemistry with potential applications in medicinal chemistry.
Preparation of Azetidinones
N-tert-Butylhydroxylamine hydrochloride has been utilised in the synthesis of 3-spirocyclopropanated 2-azetidinones, contributing to the development of novel heterocyclic compounds.
| Molecular weight | 125.60 |
|---|---|
| Linear formula | (CH3)3CNHOH · HCl |
| Assay | ≥98% |
| Application | N-tert-Butylhydroxylamine hydrochloride was used in spin trapping of short-lived radicals1. It was also used in the synthesis of α-ketoamides2 and 3-spirocyclopropanated 2-azetidinones3. |
| Melting point | 183-185 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-tert-Butylhydroxylamine hydrochloride used for?
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N-tert-Butylhydroxylamine hydrochloride is used in spin trapping of short-lived radicals, and in the synthesis of organic compounds such as α-ketoamides and 3-spirocyclopropanated 2-azetidinones.
What are the CAS number and formula for N-tert-Butylhydroxylamine hydrochloride?
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The CAS number is 57497-39-9 and the linear formula is (CH₃)₃CNHOH·HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-tert-Butylhydroxylamine hydrochloride with an assay of ≥98%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations for N-tert-Butylhydroxylamine hydrochloride?
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Handling N-tert-Butylhydroxylamine hydrochloride requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK 3 in Germany.
How is N-tert-Butylhydroxylamine hydrochloride shipped or exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals. Please contact us for specific details regarding shipping and export of N-tert-Butylhydroxylamine hydrochloride.
How can I request a sample or quote for N-tert-Butylhydroxylamine hydrochloride?
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To request a sample or obtain a quotation for N-tert-Butylhydroxylamine hydrochloride, please contact the Tech Serve Solutions sales team via our website or by phone.
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