N-tert-Butyltrimethylsilylamine
N-tert-Butyltrimethylsilylamine (CAS 5577-67-3) is a silicon-nitrogen organic compound with a molecular weight of 145.32 g/mol. It functions as a protected amine and a key building block in organic synthesis. This reagent is valuable for introducing the tert-butylsilyl group in various chemical transformations, facilitating complex molecule construction. It is supplied by Tech Serve Solutions with a typical assay of 98% for research and chemical synthesis applications.
- IUPAC
- N-(Trimethylsilyl)-tert-butylamine
- Synonyms
- N-(Trimethylsilyl)-tert-butylamine

Organic Synthesis Building Block
N-tert-Butyltrimethylsilylamine serves as a versatile building block in the synthesis of complex organic molecules. Its silyl-protected amine functionality allows for controlled reactions and selective functional group manipulation.
Protected Amine Source
This compound acts as a source of a protected amine, where the tert-butylsilyl group can be selectively removed under specific reaction conditions. This protection strategy is crucial in multi-step syntheses to prevent unwanted side reactions.
Reagent in Organosilicon Chemistry
As an organosilicon compound, it finds applications in areas involving silicon-based chemistry. It can be used to introduce silyl functionalities or as a precursor in the development of novel materials.
| Molecular weight | 145.32 |
|---|---|
| Linear formula | (CH3)3SiNHC(CH3)3 |
| Assay | 98% |
| Boiling point | 118-119 °C(lit.) |
| Density | 0.762 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.406(lit.) |


Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 26 °C / 78.8 °F |
| Transport (UN / ADR) | UN 2733PSN1 8(3) / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-tert-Butyltrimethylsilylamine used for?
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N-tert-Butyltrimethylsilylamine is primarily used as a building block in organic synthesis and as a protected amine source for introducing the tert-butylsilyl group in chemical transformations.
What are the CAS number and formula for N-tert-Butyltrimethylsilylamine?
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The CAS number for N-tert-Butyltrimethylsilylamine is 5577-67-3. Its linear formula is (CH3)3SiNHC(CH3)3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-tert-Butyltrimethylsilylamine with a typical assay of 98%. This product is supplied for laboratory and research use and is not intended for pharmaceutical, human, or animal consumption.
How should N-tert-Butyltrimethylsilylamine be handled?
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N-tert-Butyltrimethylsilylamine is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). Handle with extreme caution, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.
Is N-tert-Butyltrimethylsilylamine flammable?
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Yes, N-tert-Butyltrimethylsilylamine is a flammable liquid and vapour with a flash point of 26 °C (78.8 °F), indicated by hazard statement H226. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources.
How is this chemical packed and shipped?
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N-tert-Butyltrimethylsilylamine is packed according to transport regulations, including UN 2733, for safe shipping. Tech Serve Solutions exports this chemical globally, adhering to all relevant international shipping and handling guidelines.
How can I request a quote or sample?
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To request a quote or sample of N-tert-Butyltrimethylsilylamine, please contact our sales team through the website or by phone. Our representatives will be pleased to assist you with your inquiry.
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