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N-tert-Butyltrimethylsilylamine

CAS 5577-67-3(CH3)3SiNHC(CH3)3Organic Building Blocks

N-tert-Butyltrimethylsilylamine (CAS 5577-67-3) is a silicon-nitrogen organic compound with a molecular weight of 145.32 g/mol. It functions as a protected amine and a key building block in organic synthesis. This reagent is valuable for introducing the tert-butylsilyl group in various chemical transformations, facilitating complex molecule construction. It is supplied by Tech Serve Solutions with a typical assay of 98% for research and chemical synthesis applications.

IUPAC
N-(Trimethylsilyl)-tert-butylamine
Synonyms
N-(Trimethylsilyl)-tert-butylamine
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N-tert-Butyltrimethylsilylamine ((CH3)3SiNHC(CH3)3) — chemical structure, CAS 5577-67-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksChemical SynthesisNitrogen CompoundsOrganic Building BlocksProtected Amines
01 /Applications

Organic Synthesis Building Block

N-tert-Butyltrimethylsilylamine serves as a versatile building block in the synthesis of complex organic molecules. Its silyl-protected amine functionality allows for controlled reactions and selective functional group manipulation.

Protected Amine Source

This compound acts as a source of a protected amine, where the tert-butylsilyl group can be selectively removed under specific reaction conditions. This protection strategy is crucial in multi-step syntheses to prevent unwanted side reactions.

Reagent in Organosilicon Chemistry

As an organosilicon compound, it finds applications in areas involving silicon-based chemistry. It can be used to introduce silyl functionalities or as a precursor in the development of novel materials.

02 /Properties
Molecular weight145.32
Linear formula(CH3)3SiNHC(CH3)3
Assay98%
Boiling point118-119 °C(lit.)
Density0.762 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.406(lit.)
03 /Safety & handling
GHS hazard pictogram: Flammable (GHS02)
Flammable
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H226Flammable liquid and vapour
  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point26 °C / 78.8 °F
Transport (UN / ADR)UN 2733PSN1 8(3) / PGIII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)10-34
Safety statements (S)16-26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
5577-67-3
MDL number
MFCD00054891
PubChem substance
24862959
Beilstein registry
1734528
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-tert-Butyltrimethylsilylamine used for?

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N-tert-Butyltrimethylsilylamine is primarily used as a building block in organic synthesis and as a protected amine source for introducing the tert-butylsilyl group in chemical transformations.

What are the CAS number and formula for N-tert-Butyltrimethylsilylamine?

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The CAS number for N-tert-Butyltrimethylsilylamine is 5577-67-3. Its linear formula is (CH3)3SiNHC(CH3)3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies N-tert-Butyltrimethylsilylamine with a typical assay of 98%. This product is supplied for laboratory and research use and is not intended for pharmaceutical, human, or animal consumption.

How should N-tert-Butyltrimethylsilylamine be handled?

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N-tert-Butyltrimethylsilylamine is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). Handle with extreme caution, using appropriate personal protective equipment including gloves, eye protection, and respiratory protection in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling instructions.

Is N-tert-Butyltrimethylsilylamine flammable?

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Yes, N-tert-Butyltrimethylsilylamine is a flammable liquid and vapour with a flash point of 26 °C (78.8 °F), indicated by hazard statement H226. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources.

How is this chemical packed and shipped?

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N-tert-Butyltrimethylsilylamine is packed according to transport regulations, including UN 2733, for safe shipping. Tech Serve Solutions exports this chemical globally, adhering to all relevant international shipping and handling guidelines.

How can I request a quote or sample?

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To request a quote or sample of N-tert-Butyltrimethylsilylamine, please contact our sales team through the website or by phone. Our representatives will be pleased to assist you with your inquiry.

Need N-tert-Butyltrimethylsilylamine in a specific grade or volume?