3,6-Difluorophthalic anhydride
3,6-Difluorophthalic anhydride (CAS 652-40-4) is a difluorinated aromatic anhydride with the molecular formula C8H2F2O3 and a molecular weight of 184.10 g/mol. It is characterised by its two fluorine atoms substituted onto the phthalic anhydride ring, influencing its reactivity and properties. This compound serves as a valuable building block in organic synthesis and finds application in the development of advanced materials and polymers.
- Synonyms
- C8H2F2O3

Polymer Synthesis
3,6-Difluorophthalic anhydride can be used as a monomer in the synthesis of specialty polymers. Its incorporation can impart unique thermal, mechanical, and optical properties to the resulting polymeric materials.
Organic Intermediates
This compound acts as a versatile intermediate in the preparation of various complex organic molecules. Its anhydride functionality allows for diverse reactions, including esterification and amidation.
Materials Science
It is employed in materials science research for the development of novel functional materials. The difluoro substitution can influence electronic properties and solubility, making it suitable for advanced applications.
| Molecular weight | 184.10 |
|---|---|
| Empirical formula | C8H2F2O3 |
| Assay | 97% |
| Melting point | 218-221 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,6-Difluorophthalic anhydride used for?
+
3,6-Difluorophthalic anhydride is primarily used as a monomer in polymer synthesis and as an intermediate in organic chemistry for creating complex molecules and functional materials.
What are the CAS number and formula for 3,6-Difluorophthalic anhydride?
+
The CAS number is 652-40-4 and the empirical formula is C8H2F2O3.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,6-Difluorophthalic anhydride with an assay of 97%. This is a technical grade for research and industrial applications; it is not supplied as USP, BP, or EP grade.
How should 3,6-Difluorophthalic anhydride be handled?
+
Handle with care, avoiding dust formation and inhalation. Use a dust mask type N95 (US), wear safety eyeshields and gloves. Ensure adequate ventilation. Refer to the Safety Data Sheet for comprehensive handling information.
Is 3,6-Difluorophthalic anhydride a controlled substance?
+
Based on the provided data, there is no indication that 3,6-Difluorophthalic anhydride is a controlled substance.
How is 3,6-Difluorophthalic anhydride packed and exported?
+
3,6-Difluorophthalic anhydride is carefully packed to ensure safe transit and is available for export globally by Tech Serve Solutions.
How can I request a quote or sample for 3,6-Difluorophthalic anhydride?
+
Please contact our sales team via the website or direct enquiry to request a quote or sample for 3,6-Difluorophthalic anhydride.
▶ Related products

(2,3-Epoxypropyl)benzene
Polymer Science

(2-Boc-amino)ethyl methacrylate
C11H19NO4
Polymer Science
(3,5,5-Trimethylcyclohex-2-enylidene)malononitrile
Polymer Science

(3-Acrylamidopropyl)trimethylammonium chloride solution
Polymer Science

1,1,1-Trifluoro-2-(trifluoromethyl)-2-hydroxy-4-methyl-5-pentyl methacrylate
Polymer Science

1,1,1-Tris(4-hydroxyphenyl)ethane
Polymer Science

1,1-Cyclohexanediacetic acid
Polymer Science

1,12-Diisocyanatododecane
Polymer Science
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis