Puromycin aminonucleoside

CAS 58-60-6C12H18N6O3Biochemicals & Reagents

Puromycin aminonucleoside (CAS: 58-60-6), with the molecular formula C12H18N6O3, is a nucleoside antibiotic. It functions as a potent inhibitor of protein synthesis by causing premature chain termination during translation. This property makes it a valuable tool in molecular biology research for studying the mechanisms of protein synthesis and for investigating cellular processes. Supplied by TSS, it is a PREMIUM grade reagent.

IUPAC: 3′-Amino-3′-deoxy-N6,N6-dimethyladenosine

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Puromycin aminonucleoside (C12H18N6O3) — chemical structure, CAS 58-60-6; Life Science, fine chemical supplied by Tech Serve Solutions

AntibacterialAntibioticsAntibiotics A to ZAntibiotics N-SAntibiotics by ApplicationBiochemicals and ReagentsCore BioreagentsGenetic Marker SelectionMechanism of ActionResearch Essentials

01 /Applications

Protein Synthesis Inhibition

Puromycin aminonucleoside is widely used in research laboratories to study the intricate mechanisms of protein synthesis. Its ability to cause premature termination of polypeptide chains allows researchers to investigate translation fidelity and dynamics.

Cellular Biology Research

This compound serves as an essential reagent for exploring various cellular processes, including cell proliferation and differentiation. Its impact on protein synthesis makes it useful for studying the effects of translation inhibition on cell behaviour.

Antibacterial and Antineoplastic Studies

As an antibiotic, puromycin aminonucleoside has been investigated for its antibacterial properties and potential as an antineoplastic agent. Its mechanism of interfering with protein synthesis is a key area of study in these fields.

02 /Properties

Molecular weight	294.31
Empirical formula	C12H18N6O3
Assay	≥99.0% (HPLC)
Solubility	H2O: soluble50 mg/mL, clear, slightly yellow
Storage temperature	2-8°C

03 /Safety & handling

GHS hazard pictogram: Health hazard (GHS08) — Health hazard

Warning

Hazard statements

H373May cause damage to organs through prolonged exposure

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xn
Risk statements (R)	48/22

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

58-60-6

MDL number

MFCD00063462

PubChem substance

24898823

Beilstein registry

93902

05 /Additional specifications

Quality Level	PREMIUM
Target Organs	Kidney

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is Puromycin aminonucleoside used for?

Puromycin aminonucleoside is primarily used in research laboratories to inhibit protein synthesis, enabling studies into translation mechanisms, cellular processes, and its potential antibacterial and antineoplastic activities.

What are the CAS number and formula for Puromycin aminonucleoside?

The CAS number for Puromycin aminonucleoside is 58-60-6, and its molecular formula is C12H18N6O3.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Puromycin aminonucleoside at PREMIUM grade with an assay of ≥99.0% (HPLC). We do not represent this product as USP, BP, or EP grade.

How should Puromycin aminonucleoside be handled safely?

Puromycin aminonucleoside may cause damage to organs through prolonged or repeated exposure (H373). Handle with care, using appropriate personal protective equipment including eyeshields, gloves, and a P1 respirator filter. Store at 2-8°C.