3-(4-Morpholinomethyl)phenylboronic acid pinacol ester
3-(4-Morpholinomethyl)phenylboronic acid pinacol ester (CAS: 364794-80-9) is an organoboron compound with the molecular formula C17H26BNO3 and a molecular weight of 303.20 g/mol. This aryl boronate ester is a valuable building block in organic synthesis, particularly for cross-coupling reactions. It serves as a reagent for introducing the morpholinomethylphenyl moiety into complex molecules, finding utility in pharmaceutical research and development and materials science.
- IUPAC
- 3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2-yl)benzyl]morpholine
- Synonyms
- 3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2-yl)benzyl]morpholine
Suzuki-Miyaura Coupling Reagent
This pinacol ester derivative is a key substrate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds with aryl or vinyl halides and pseudohalides. Its structure allows for efficient coupling to introduce substituted phenyl rings into organic frameworks.
Pharmaceutical Intermediate
The compound can serve as an intermediate in the synthesis of pharmacologically active compounds. The morpholine and phenylboronate ester functionalities offer versatile points for further chemical modification, aiding in the development of novel drug candidates.
Materials Science Applications
Organoboron compounds like this are explored for their use in creating novel materials, including organic light-emitting diodes (OLEDs) and other functional organic materials. The specific electronic and structural properties can be tuned through further synthetic modifications.
| Molecular weight | 303.20 |
|---|---|
| Empirical formula | C17H26BNO3 |
| Assay | 95% |
| Melting point | 52-56 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3-(4-Morpholinomethyl)phenylboronic acid pinacol ester used for?
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It is primarily used as a building block in organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. It also finds application as an intermediate in pharmaceutical research and development and in materials science.
What is the CAS number and formula for this compound?
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The CAS number is 364794-80-9 and the empirical formula (Hill notation) is C17H26BNO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a minimum purity of 95% (assay). We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this chemical?
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This compound requires the use of eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Handle in a well-ventilated area to avoid breathing dust. The flash point is greater than 110 °C.
How is 3-(4-Morpholinomethyl)phenylboronic acid pinacol ester packed, shipped, and exported?
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Tech Serve Solutions professionally packs, ships, and exports chemicals globally, adhering to all relevant transportation and customs regulations to ensure safe and compliant delivery worldwide.
How can I request a sample or a quote for this product?
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To request a sample or a quote, please contact our sales team through the website or by phone, providing the product name and CAS number (364794-80-9).
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