3,4-Dimethoxyphenylmagnesium bromide solution
3,4-Dimethoxyphenylmagnesium bromide solution (CAS: 89980-69-8) is an organometallic reagent with the linear formula (CH3O)2C6H3MgBr and a molecular weight of 241.36 g/mol. Supplied as a 0.5 M solution in Tetrahydrofuran (THF), this Grignard reagent is primarily utilised in organic synthesis for the introduction of the 3,4-dimethoxyphenyl group into target molecules. Its reactivity makes it a valuable tool in the preparation of complex organic structures and pharmaceutical intermediates.
- Synonyms
- (CH3O)2C6H3MgBr
Grignard Reagent in Organic Synthesis
Utilised as a nucleophilic source of the 3,4-dimethoxyphenyl moiety in carbon-carbon bond formation reactions. It reacts with various electrophiles such as aldehydes, ketones, esters, and epoxides to construct more complex molecular architectures.
Synthesis of Pharmaceutical Intermediates
Serves as a key building block in the multi-step synthesis of various biologically active compounds and pharmaceutical intermediates. Its specific structure is found in numerous natural products and drug candidates.
Preparation of Fine Chemicals
Employed in the synthesis of specialised fine chemicals and research compounds where the 3,4-dimethoxyphenyl fragment is a required structural element.
| Molecular weight | 241.36 |
|---|---|
| Linear formula | (CH3O)2C6H3MgBr |
| Boiling point | 65 °C |
| Density | 0.960 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxyphenylmagnesium bromide solution used for?
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3,4-Dimethoxyphenylmagnesium bromide solution is primarily used as a Grignard reagent in organic synthesis to introduce the 3,4-dimethoxyphenyl group into target molecules, often in the preparation of pharmaceutical intermediates and fine chemicals.
What are the CAS number and formula for 3,4-Dimethoxyphenylmagnesium bromide solution?
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The CAS number is 89980-69-8 and the linear formula is (CH3O)2C6H3MgBr.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxyphenylmagnesium bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP, BP, EP or other pharmacopoeial grades.
How should 3,4-Dimethoxyphenylmagnesium bromide solution be handled?
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This solution is flammable and can cause serious eye irritation and may cause respiratory irritation. It may also be carcinogenic. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. May form explosive peroxides. Consult the Safety Data Sheet (SDS) for full hazard information and handling procedures.
How is this chemical packed, shipped, and exported?
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Tech Serve Solutions expertly packs, ships, and exports chemicals globally, adhering to all relevant regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for 3,4-Dimethoxyphenylmagnesium bromide solution?
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To request a sample or a quote, please contact our sales team through the website or by calling us directly. Please specify the quantity and destination for your request.
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