3,4-Dimethoxyphenol
3,4-Dimethoxyphenol (CAS: 2033-89-8) is an organic compound with the linear formula (CH3O)2C6H3OH and a molecular weight of 154.16 g/mol. This phenol derivative is primarily utilised as a building block in organic synthesis, contributing to the creation of more complex molecules. It is supplied by Tech Serve Solutions with an assay of 97% and is suitable for research and chemical synthesis applications.
- Synonyms
- (CH3O)2C6H3OH

Synthesis of Benzofuranone Derivatives
3,4-Dimethoxyphenol serves as a precursor in the synthesis of 5,6-dimethoxy benzofuranone derivatives. These compounds have been investigated for their potential as multi-target anti-Alzheimer agents, highlighting its role in medicinal chemistry research.
Preparation of Glucopyranosides
The compound is employed in the preparation of 3,4-dimethoxyphenyl-β-D-glucopyranoside. This application demonstrates its utility in synthesising glycoside structures, which are relevant in various areas of organic and carbohydrate chemistry.
Alkylation Reactions
3,4-Dimethoxyphenol can be used in alkylation reactions, such as the synthesis of 4-(but-2-enyloxy)-1,2-dimethoxybenzene. This showcases its ability to participate in ether formation, a fundamental transformation in organic synthesis.
Chromene Synthesis
It acts as a precursor for the synthesis of 4H-chromenes. This application underscores its value as a versatile building block for constructing heterocyclic ring systems important in pharmaceutical and materials science.
| Molecular weight | 154.16 |
|---|---|
| Linear formula | (CH3O)2C6H3OH |
| Assay | 97% |
| Application | 3,4-Dimethoxyphenol was used in the synthesis of:• 5,6-dimethoxy benzofuranone derivatives, multi-target anti Alzheimer compounds1• 3,4-dimethoxyphenyl-β-D-glucopyranoside2• 4-(but-2-enyloxy)-1,2-dimethoxybenzene3• precursors for the synthesis of the 4H-chromenes3 |
| Melting point | 79-82 °C(lit.) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,4-Dimethoxyphenol used for?
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3,4-Dimethoxyphenol is primarily used as a building block in organic synthesis for the preparation of various chemical compounds, including benzofuranone derivatives, glucopyranosides, and chromenes, often in research and development settings.
What are the CAS number and formula for 3,4-Dimethoxyphenol?
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The CAS number for 3,4-Dimethoxyphenol is 2033-89-8, and its linear formula is (CH3O)2C6H3OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 3,4-Dimethoxyphenol with an assay of 97%. We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
What are the safety and handling precautions for 3,4-Dimethoxyphenol?
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3,4-Dimethoxyphenol is classified as a Warning substance. It causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, gloves, and a dust mask type N95 (US), should be used. Handle in a well-ventilated area.
Is 3,4-Dimethoxyphenol a controlled substance?
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The provided data does not indicate that 3,4-Dimethoxyphenol is a controlled substance.
How is 3,4-Dimethoxyphenol shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals. Specific shipping and export details for 3,4-Dimethoxyphenol can be provided upon request.
How can I request a sample or quote for 3,4-Dimethoxyphenol?
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To request a sample or a quote for 3,4-Dimethoxyphenol, please contact our sales team through the channels provided on the Tech Serve Solutions website.
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