2-Tributylstannylthiazole
2-Tributylstannylthiazole (CAS 121359-48-6), with the empirical formula C15H29NSSn and a molecular weight of 374.17 g/mol, is an organometallic reagent. It is primarily utilised as a reactant in Stille cross-coupling reactions for the arylation of thiazole moieties. This compound is supplied by Tech Serve Solutions for chemical synthesis and research purposes.
Stille Cross-Coupling Reactions
2-Tributylstannylthiazole serves as a key organotin reagent in Stille cross-coupling reactions. It facilitates the efficient arylation of thiazole derivatives, a crucial transformation in organic synthesis.
Heterocyclic Chemistry
This compound is valuable in the synthesis of complex heterocyclic structures containing the thiazole ring. Its application enables the introduction of thiazole fragments into various molecular frameworks.
Organic Synthesis Reagent
As an organometallic reagent, 2-Tributylstannylthiazole is employed in advanced organic synthesis protocols. It provides a reliable method for forming carbon-carbon bonds with aryl or vinyl halides.
| Molecular weight | 374.17 |
|---|---|
| Empirical formula | C15H29NSSn |
| Assay | 97% |
| Boiling point | 307-309 °C(lit.) |
| Density | 1.1900 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5200(lit.) |
| Application | Reagent for arylation of thiazole by Stille cross-coupling.1 |
Hazard statements
- H301Toxic if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H372Causes damage to organs through prolonged exposure
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
- P314Get medical attention if you feel unwell
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 2788 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T,N |
| Risk statements (R) | 21-25-36/38-48/23/25-50/53 |
| Safety statements (S) | 35-36/37/39-45-60-61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Tributylstannylthiazole used for?
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2-Tributylstannylthiazole is used as a reagent in Stille cross-coupling reactions for the arylation of thiazole.
What is the CAS number and formula for 2-Tributylstannylthiazole?
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The CAS number is 121359-48-6, and the empirical formula is C15H29NSSn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Tributylstannylthiazole with an assay of 97%. This product is not represented as USP, BP, or EP grade.
How should 2-Tributylstannylthiazole be handled?
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2-Tributylstannylthiazole is a dangerous substance. It is toxic if swallowed or in contact with skin, causes skin and serious eye irritation, and may cause damage to organs through prolonged or repeated exposure. It is also very toxic to aquatic life with long-lasting effects. Handle with appropriate personal protective equipment, including eyeshields, face shields, gloves, and a suitable respirator. Ensure adequate ventilation and avoid release to the environment.
Is 2-Tributylstannylthiazole available for international export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Tributylstannylthiazole.
How can I request a sample or quote for 2-Tributylstannylthiazole?
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Please contact our sales team through the website or by phone to request a sample or a quotation for 2-Tributylstannylthiazole.
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