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2-Thiophenesulfonyl chloride

CAS 16629-19-9C4H3ClO2S2Chemical Synthesis

2-Thiophenesulfonyl chloride (CAS: 16629-19-9) is a chemical compound with the formula C4H3ClO2S2 and a molecular weight of 182.65 g/mol. As a reactive sulfonyl chloride derivative of thiophene, it serves as a valuable building block in organic synthesis. It is primarily utilised in the preparation of more complex molecules, particularly within the fields of chemical synthesis and heterocyclic chemistry.

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2-Thiophenesulfonyl chloride (C4H3ClO2S2) — chemical structure, CAS 16629-19-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Building BlocksC4 to C6Chemical SynthesisHeterocyclic Building BlocksThiophenes
01 /Applications

Organic Synthesis Reagent

2-Thiophenesulfonyl chloride is employed as a key intermediate in the synthesis of various organic compounds. Its reactive sulfonyl chloride group allows for facile derivatization.

Preparation of Thiophene Derivatives

This compound has been specifically utilised in the preparation of novel thiophene-containing molecules, such as 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene.

Heterocyclic Chemistry

As a thiophene derivative, it is a useful reagent in heterocyclic chemistry for constructing complex structures with sulfur-containing rings.

02 /Properties
Molecular weight182.65
Empirical formulaC4H3ClO2S2
Assay96%
Boiling point130-132 °C/14 mmHg(lit.)
Application2-Thiophenesulfonyl chloride has been used in the preparation of 2-((trans-2-phenyl cyclopropyl)sulfonyl)thiophene1.
Melting point30-32 °C(lit.)
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3261 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
16629-19-9
MDL number
MFCD00005426
PubChem substance
24855415
Beilstein registry
123536
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is 2-Thiophenesulfonyl chloride used for?

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2-Thiophenesulfonyl chloride is used as a building block in organic synthesis, particularly for preparing thiophene derivatives and in heterocyclic chemistry.

What is the CAS number and chemical formula for 2-Thiophenesulfonyl chloride?

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The CAS number is 16629-19-9 and the chemical formula is C4H3ClO2S2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies 2-Thiophenesulfonyl chloride with a minimum assay of 96%. This is suitable for research and general chemical synthesis; TSS does not represent it as USP, BP, or EP grade.

How should 2-Thiophenesulfonyl chloride be handled safely?

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2-Thiophenesulfonyl chloride is corrosive and causes severe skin burns and eye damage (H314). Handle with appropriate personal protective equipment, including eyeshields, face shields, chemical-resistant gloves, and respiratory protection suitable for corrosive vapours. Ensure adequate ventilation.

Is 2-Thiophenesulfonyl chloride a controlled substance?

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The provided data does not indicate that 2-Thiophenesulfonyl chloride (CAS: 16629-19-9) is a controlled substance.

How is 2-Thiophenesulfonyl chloride shipped?

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2-Thiophenesulfonyl chloride is shipped according to UN 3261, Class 8, Packing Group II regulations for corrosive materials. TSS exports globally.

How can I request a quote or sample for 2-Thiophenesulfonyl chloride?

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Please contact our sales team via the website or phone to request a quote or sample for 2-Thiophenesulfonyl chloride.

Need 2-Thiophenesulfonyl chloride in a specific grade or volume?